U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    KDM1A lysine demethylase 1A [ Bos taurus (domestic cattle) ]

    Gene ID: 532997, updated on 29-Jan-2025

    Summary

    Go to the top of the page Help
    Official Symbol
    KDM1Aprovided by VGNC
    Official Full Name
    lysine demethylase 1Aprovided by VGNC
    Primary source
    VGNC:VGNC:30522
    See related
    BGD:BT22323; Ensembl:ENSBTAG00000009500
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    AOF2; KDM1
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See KDM1A in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (129769935..129836280, complement)

    Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene 5-hydroxytryptamine receptor 1D Neighboring gene leucine zipper protein 1 Neighboring gene testis expressed 46 Neighboring gene lactamase beta like 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables chromatin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription factor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    lysine-specific histone demethylase 1A
    Names
    amine oxidase (flavin containing) domain 2
    lysine (K)-specific demethylase 1
    XP_002685763.1
    XP_005203376.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      129769935..129836280 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002685717.5 → XP_002685763.1  lysine-specific histone demethylase 1A isoform X2

      See identical proteins and their annotated locations for XP_002685763.1

      UniProtKB/TrEMBL
      A0A3Q1NET3
      Related
      ENSBTAP00070011043.1, ENSBTAT00070018767.1
      Conserved Domains (5) summary
      pfam01391
      Location:42 → 97
      Collagen; Collagen triple helix repeat (20 copies)
      smart00150
      Location:411 → 513
      SPEC; Spectrin repeats
      pfam01593
      Location:289 → 826
      Amino_oxidase; Flavin containing amine oxidoreductase
      pfam04433
      Location:178 → 265
      SWIRM; SWIRM domain
      pfam13450
      Location:284 → 342
      NAD_binding_8; NAD(P)-binding Rossmann-like domain

    2. XM_005203319.3 → XP_005203376.1  lysine-specific histone demethylase 1A isoform X1

      See identical proteins and their annotated locations for XP_005203376.1

      UniProtKB/TrEMBL
      A0A3Q1NET3
      Related
      ENSBTAP00070010953.1, ENSBTAT00070018672.1
      Conserved Domains (5) summary
      pfam01391
      Location:42 → 97
      Collagen; Collagen triple helix repeat (20 copies)
      pfam01593
      Location:309 → 846
      Amino_oxidase; Flavin containing amine oxidoreductase
      pfam04433
      Location:198 → 285
      SWIRM; SWIRM domain
      pfam13450
      Location:304 → 362
      NAD_binding_8; NAD(P)-binding Rossmann-like domain
      cl21568
      Location:396 → 492
      SurA_N_3; SurA N-terminal domain
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.