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    HDGFL2 HDGF like 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 512959, updated on 30-Jan-2025

    Summary

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    Official Symbol
    HDGFL2provided by VGNC
    Official Full Name
    HDGF like 2provided by VGNC
    Primary source
    VGNC:VGNC:109383
    See related
    EnsemblRapid:ENSBTAG00070014032
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    HDGF2; HDGFRP2
    Orthologs
    human mouse all
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    Genomic context

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    See HDGFL2 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (19628203..19645456, complement)

    Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene leucine rich alpha-2-glycoprotein 1 Neighboring gene perilipin 5 Neighboring gene perilipin 4 Neighboring gene uncharacterized LOC101902724 Neighboring gene UBX domain protein 6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC165989

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables H3K27me3 modified histone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables H3K9me3 modified histone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hepatoma-derived growth factor-related protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105361.1 → NP_001098831.1  hepatoma-derived growth factor-related protein 2

      See identical proteins and their annotated locations for NP_001098831.1

      Status: PROVISIONAL

      Source sequence(s)
      BC153286
      UniProtKB/TrEMBL
      A7Z084
      Related
      ENSBTAP00070018711.1, ENSBTAT00070031731.1
      Conserved Domains (1) summary
      pfam11467
      Location:349 → 437
      LEDGF; Lens epithelium-derived growth factor (LEDGF)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      19628203..19645456 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024994149.2 → XP_024849917.1  hepatoma-derived growth factor-related protein 2 isoform X1

      Conserved Domains (2) summary
      cd05834
      Location:3 → 87
      HDGF_related; The PWWP domain is an essential part of the Hepatoma Derived Growth Factor (HDGF) family of proteins, and is necessary for DNA binding by HDGF. This family of endogenous nuclear-targeted mitogens includes HRP (HDGF-related proteins 1, 2, 3, 4, or HPR1, ...
      pfam11467
      Location:470 → 558
      LEDGF; Lens epithelium-derived growth factor (LEDGF)

    2. XM_005208938.5 → XP_005208995.2  hepatoma-derived growth factor-related protein 2 isoform X2

      UniProtKB/TrEMBL
      A7Z084
      Conserved Domains (1) summary
      pfam11467
      Location:349 → 437
      LEDGF; Lens epithelium-derived growth factor (LEDGF)
    Nucleotide Protein Strain
    Heading Accession and Version

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