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    Ints5 integrator complex subunit 5 [ Mus musculus (house mouse) ]

    Gene ID: 109077, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ints5provided by MGI
    Official Full Name
    integrator complex subunit 5provided by MGI
    Primary source
    MGI:MGI:1923578
    See related
    Ensembl:ENSMUSG00000071652 AllianceGenome:MGI:1923578
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mKIAA1698; 1110055N21Rik
    Summary
    Predicted to be involved in snRNA 3'-end processing. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of integrator complex. Is expressed in forebrain. Orthologous to human INTS5 (integrator complex subunit 5). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in thymus adult (RPKM 17.6), ovary adult (RPKM 16.9) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Ints5 in Genome Data Viewer
    Location:
    19 A; 19 5.95 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (8870351..8875254)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (8892987..8897890)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 5730408K05 gene Neighboring gene LBH domain containing 1 Neighboring gene RIKEN cDNA 1810009A15 gene Neighboring gene STARR-positive B cell enhancer ABC_E11017 Neighboring gene microRNA 5136 Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:8967434-8967543 Neighboring gene STARR-positive B cell enhancer ABC_E4265 Neighboring gene alpha glucosidase 2 alpha neutral subunit Neighboring gene STARR-seq mESC enhancer starr_45501 Neighboring gene predicted gene, 36629 Neighboring gene beta-1,3-glucuronyltransferase 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in snRNA 3'-end processing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in snRNA processing ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in snRNA processing ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    part_of integrator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of integrator complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of integrator complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nuclear membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    integrator complex subunit 5
    Names
    int5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_176843.3NP_789813.1  integrator complex subunit 5

      See identical proteins and their annotated locations for NP_789813.1

      Status: VALIDATED

      Source sequence(s)
      AC129217, AK168795, BY152900, BY546950
      Consensus CDS
      CCDS29556.1
      UniProtKB/Swiss-Prot
      Q3TM44, Q8CHT3
      Related
      ENSMUSP00000093968.6, ENSMUST00000096249.7
      Conserved Domains (2) summary
      pfam14837
      Location:29251
      INTS5_N; Integrator complex subunit 5 N-terminus
      pfam14838
      Location:289998
      INTS5_C; Integrator complex subunit 5 C-terminus

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      8870351..8875254
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)