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    Zfp330 zinc finger protein 330 [ Mus musculus (house mouse) ]

    Gene ID: 30932, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Zfp330provided by MGI
    Official Full Name
    zinc finger protein 330provided by MGI
    Primary source
    MGI:MGI:1353574
    See related
    Ensembl:ENSMUSG00000031711 AllianceGenome:MGI:1353574
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Noa36; Znf330
    Summary
    Predicted to enable zinc ion binding activity. Predicted to be located in chromosome, centromeric region; midbody; and nuclear lumen. Predicted to be active in nucleus. Is expressed in central nervous system and genitourinary system. Orthologous to human ZNF330 (zinc finger protein 330). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 25.6), CNS E18 (RPKM 18.9) and 24 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Zfp330 in Genome Data Viewer
    Location:
    8 C2; 8 39.58 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (83490247..83500774, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (82763618..82774145, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene STARR-positive B cell enhancer mm9_chr8:85268437-85268738 Neighboring gene STARR-seq mESC enhancer starr_22068 Neighboring gene STARR-positive B cell enhancer ABC_E5023 Neighboring gene STARR-seq mESC enhancer starr_22070 Neighboring gene heat shock protein 1 (chaperonin) pseudogene 5 Neighboring gene predicted gene, 31545 Neighboring gene ring finger protein 150 Neighboring gene predicted gene, 46045

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning of a zinc finger autoantigen transiently associated with interphase nucleolus and mitotic centromeres and midbodies. Orthologous proteins with nine CXXC motifs highly conserved from nematodes to humans. Bolívar J, et al. J Biol Chem, 1999 Dec 17. PMID 10593942
    2. An Interaction Landscape of Ubiquitin Signaling. Zhang X, et al. Mol Cell, 2017 Mar 2. PMID 28190767
    3. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    4. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
    5. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Clone Names

    • MGC6718, MGC41503, MGC103365

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chromosome, centromeric region ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in chromosome, centromeric region ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in midbody ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in midbody ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleolus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 330
    Names
    nucleolar autoantigen 36
    nucleolar cysteine-rich protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001368343.1 → NP_001355272.1  zinc finger protein 330 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC124757

    2. NM_001368344.1 → NP_001355273.1  zinc finger protein 330 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC124757

    3. NM_001368345.1 → NP_001355274.1  zinc finger protein 330 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC124757

    4. NM_001368346.1 → NP_001355275.1  zinc finger protein 330 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC124757

    5. NM_145600.2 → NP_663575.1  zinc finger protein 330 isoform 1

      See identical proteins and their annotated locations for NP_663575.1

      Status: VALIDATED

      Source sequence(s)
      AC124757
      Consensus CDS
      CCDS22447.1
      UniProtKB/Swiss-Prot
      Q8C389, Q8K2M4, Q922H9
      Related
      ENSMUSP00000034147.4, ENSMUST00000034147.4
      Conserved Domains (1) summary
      pfam06524
      Location:1 → 290
      NOA36; NOA36 protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      83490247..83500774 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q922H9.1 GenPept UniProtKB/Swiss-Prot:Q922H9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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