Vps26c VPS26 endosomal protein sorting factor C [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Vps26cprovided by MGI
Official Full Name: VPS26 endosomal protein sorting factor Cprovided by MGI
Primary source: MGI:MGI:1206040
See related: Ensembl:ENSMUSG00000022898 AllianceGenome:MGI:1206040
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Dcra; Dscr3
Summary: Predicted to be involved in endocytic recycling and intracellular protein transport. Predicted to be active in endosome. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Orthologous to human VPS26C (VPS26 endosomal protein sorting factor C). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Ubiquitous expression in placenta adult (RPKM 34.4), CNS E18 (RPKM 22.7) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 16 C4; 16 55.23 cM

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	16	NC_000082.7 (94298583..94327488, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	16	NC_000082.6 (94497724..94526629, complement)

Chromosome 16 - NC_000082.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

General gene information

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Markers

Dscr3 (e-PCR), detects polymorphism
- UniSTS:259074

Dscr3 (e-PCR), detects polymorphism
- UniSTS:259606

Dscr3 (e-PCR), detects polymorphism
- UniSTS:507936

RH144357 (e-PCR)
- UniSTS:233602

AW538125 (e-PCR)
- UniSTS:180952

Gene Ontology Provided by MGI

Process	Evidence Code	Pubs
involved_in endocytic recycling	ISO Inferred from Sequence Orthology more info
involved_in endocytic recycling	ISS Inferred from Sequence or Structural Similarity more info
involved_in intracellular protein transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in intracellular protein transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in endosome	IBA Inferred from Biological aspect of Ancestor more info
located_in endosome	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: vacuolar protein sorting-associated protein 26C

Names: DSCR3 arrestin fold containing; Down syndrome critical region gene 3; Down syndrome critical region gene A; Down syndrome critical region protein 3 homolog; Down syndrome critical region protein A homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.