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    Myt1l myelin transcription factor 1-like [ Mus musculus (house mouse) ]

    Gene ID: 17933, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Myt1lprovided by MGI
    Official Full Name
    myelin transcription factor 1-likeprovided by MGI
    Primary source
    MGI:MGI:1100511
    See related
    Ensembl:ENSMUSG00000061911 AllianceGenome:MGI:1100511
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Nztf1; Pmng1; Png-1; mKIAA1106; 2900046C06Rik; 2900093J19Rik; C630034G21Rik
    Summary
    Enables DNA-binding transcription repressor activity, RNA polymerase II-specific. Involved in negative regulation of transcription by RNA polymerase II; neuron development; and neuron fate specification. Located in nucleus. Is expressed in several structures, including eye; genitourinary system; nervous system; and olfactory epithelium. Used to study autosomal dominant intellectual developmental disorder 39. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 39. Orthologous to human MYT1L (myelin transcription factor 1 like). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in CNS E18 (RPKM 9.3), frontal lobe adult (RPKM 8.6) and 6 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Myt1l in Genome Data Viewer
    Location:
    12 A2; 12 11.86 cM
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (29578375..29973215)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (29527590..29923216)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 31650 Neighboring gene STARR-seq mESC enhancer starr_31832 Neighboring gene predicted gene, 53714 Neighboring gene predicted gene, 20208 Neighboring gene STARR-seq mESC enhancer starr_31833 Neighboring gene STARR-seq mESC enhancer starr_31834 Neighboring gene RIKEN cDNA C630031E19 gene Neighboring gene predicted gene, 53715 Neighboring gene predicted gene, 46346 Neighboring gene predicted gene, 31939 Neighboring gene STARR-seq mESC enhancer starr_31838 Neighboring gene peroxidasin Neighboring gene STARR-seq mESC enhancer starr_31839 Neighboring gene STARR-seq mESC enhancer starr_31840 Neighboring gene predicted gene 15691 Neighboring gene thyroid peroxidase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Png-1, a nervous system-specific zinc finger gene, identifies regions containing postmitotic neurons during mammalian embryonic development. Weiner JA, et al. J Comp Neurol, 1997 May 5. PMID 9130664
    2. MYT1L is required for suppressing earlier neuronal development programs in the adult mouse brain. Chen J, et al. Genome Res, 2023 Apr. PMID 37100461, Free PMC Article
    3. Myt1L Promotes Differentiation of Oligodendrocyte Precursor Cells and is Necessary for Remyelination After Lysolecithin-Induced Demyelination. Shi Y, et al. Neurosci Bull, 2018 Apr. PMID 29397565, Free PMC Article
    4. Lysophosphatidic acid receptor gene vzg-1/lpA1/edg-2 is expressed by mature oligodendrocytes during myelination in the postnatal murine brain. Weiner JA, et al. J Comp Neurol, 1998 Sep 7. PMID 9717712
    5. Myt/NZF family transcription factors regulate neuronal differentiation of P19 cells. Kameyama T, et al. Neurosci Lett, 2011 Jun 22. PMID 21540077

    See all (54) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. MYT1L haploinsufficiency in human neurons and mice causes autism-associated phenotypes that can be reversed by genetic and pharmacologic intervention.
      Title: MYT1L haploinsufficiency in human neurons and mice causes autism-associated phenotypes that can be reversed by genetic and pharmacologic intervention.
    2. MYT1L is required for suppressing earlier neuronal development programs in the adult mouse brain.
      Title: MYT1L is required for suppressing earlier neuronal development programs in the adult mouse brain.
    3. Postnatal age-differential ASD-like transcriptomic, synaptic, and behavioral deficits in Myt1l-mutant mice.
      Title: Postnatal age-differential ASD-like transcriptomic, synaptic, and behavioral deficits in Myt1l-mutant mice.
    4. Myt1l haploinsufficiency leads to obesity and multifaceted behavioral alterations in mice.
      Title: Myt1l haploinsufficiency leads to obesity and multifaceted behavioral alterations in mice.
    5. A MYT1L syndrome mouse model recapitulates patient phenotypes and reveals altered brain development due to disrupted neuronal maturation.
      Title: A MYT1L syndrome mouse model recapitulates patient phenotypes and reveals altered brain development due to disrupted neuronal maturation.
    6. our findings demonstrate that Myt1L is an essential regulator of oligodendrocyte precursor cell differentiation
      Title: Myt1L Promotes Differentiation of Oligodendrocyte Precursor Cells and is Necessary for Remyelination After Lysolecithin-Induced Demyelination.
    7. Depletion of Myt1l in primary postmitotic neurons de-repressed non-neuronal programs and impaired neuronal gene expression and function, indicating that many somatic lineage programs are actively and persistently repressed by Myt1l to maintain neuronal identity.
      Title: Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates.
    8. NZF-1 was expressed later in post-mitotic neurons. NZF-2 was initially expressed in neuronal cells a little earlier than NZF-3. NZF-3 was initially expressed in neuronal cells, just after proliferation was complete.
      Title: Spatiotemporal expression pattern of Myt/NZF family zinc finger transcription factors during mouse nervous system development.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables DNA-binding transcription activator activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables cobalt ion binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables metal ion sequestering activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables retinoic acid-responsive element binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in nervous system development IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in neuron development IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in neuron differentiation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in neuron fate commitment IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in neuron fate specification IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    myelin transcription factor 1-like protein
    Names
    NZF-1
    myT1-L
    neural zinc finger factor 1
    neural zinc finger protein NZF-1
    neural zinc finger transcription factor 1
    postmeiotic neural gene 1
    postmitotic neural gene 1 protein
    zinc finger protein Png-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001093775.1 → NP_001087244.1  myelin transcription factor 1-like protein isoform 1

      See identical proteins and their annotated locations for NP_001087244.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AK013654, BC094438, BE653129, BQ876229, CB521730, CD802997, CX240996
      Consensus CDS
      CCDS49042.1
      UniProtKB/Swiss-Prot
      A2RRK5, D3Z1P7, O08996, P97500, Q33DP0, Q8C643, Q8C7L4, Q8CHB4
      UniProtKB/TrEMBL
      Q0VGN2
      Related
      ENSMUSP00000058264.10, ENSMUST00000049784.17
      Conserved Domains (3) summary
      COG1196
      Location:1034 → 1186
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:905 → 933
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:622 → 873
      MYT1; Myelin transcription factor 1

    2. NM_001093776.1 → NP_001087245.1  myelin transcription factor 1-like protein isoform 2

      See identical proteins and their annotated locations for NP_001087245.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate in-frame splice site in the mid-coding region, compared to variant 1, resulting in a shorter protein (isoform 2). Variants 2, 3, 6 and 7 encode the same isoform (2).
      Source sequence(s)
      AK013654, BC079651, BC094438, CD352642, CX240996
      Consensus CDS
      CCDS49041.1
      UniProtKB/TrEMBL
      Q0VGN2
      Related
      ENSMUSP00000021009.9, ENSMUST00000021009.10
      Conserved Domains (3) summary
      COG1196
      Location:1032 → 1184
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:903 → 931
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:620 → 871
      MYT1; Myelin transcription factor 1

    3. NM_001093778.1 → NP_001087247.1  myelin transcription factor 1-like protein isoform 3

      See identical proteins and their annotated locations for NP_001087247.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) uses alternate in-frame splice sites in the 5' and mid-coding regions, compared to variant 1, resulting in a shorter protein (isoform 3).
      Source sequence(s)
      AK013654, BC094438, BE653129, BQ876229, CB521730, CF536651, CX240996
      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      pfam01530
      Location:902 → 928
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:619 → 870
      MYT1; Myelin transcription factor 1
      pfam10267
      Location:1054 → 1126
      Tmemb_cc2; Predicted transmembrane and coiled-coil 2 protein

    4. NM_001361655.1 → NP_001348584.1  myelin transcription factor 1-like protein isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC159626, AK013654, BB618038, BC079651, BC094438, BE653129, CD802997, CF746282, CX240996
      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      TIGR04211
      Location:1061 → 1139
      SH3_and_anchor; SH3 domain protein
      pfam01530
      Location:905 → 933
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:622 → 873
      MYT1; Myelin transcription factor 1

    5. NM_001361656.1 → NP_001348585.1  myelin transcription factor 1-like protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      AK013654, BC079651, BC094438, CJ070076, CX240996
      Consensus CDS
      CCDS49041.1
      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:1032 → 1184
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:903 → 931
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:620 → 871
      MYT1; Myelin transcription factor 1

    6. NM_001361657.1 → NP_001348586.1  myelin transcription factor 1-like protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      AK013654, BC079651, BC094438, BY124359, CX240996
      Consensus CDS
      CCDS49041.1
      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:1032 → 1184
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:903 → 931
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:620 → 871
      MYT1; Myelin transcription factor 1

    7. NM_001361658.1 → NP_001348587.1  myelin transcription factor 1-like protein isoform 5

      Status: VALIDATED

      Source sequence(s)
      AK013654, BC079651, BC094438, BE653129, CB521730, CX240996
      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:1011 → 1163
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:882 → 910
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:599 → 850
      MYT1; Myelin transcription factor 1

    8. NM_001361659.1 → NP_001348588.1  myelin transcription factor 1-like protein isoform 6

      Status: VALIDATED

      Source sequence(s)
      AK013654, BC079651, BC094438, BE653129, CB521730, CX240996
      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:987 → 1139
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:858 → 886
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:575 → 826
      MYT1; Myelin transcription factor 1

    9. NM_001361660.1 → NP_001348589.1  myelin transcription factor 1-like protein isoform 7

      Status: VALIDATED

      Source sequence(s)
      AK013654, BC079651, BC094438, BE653129, CB521730, CX240996
      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:984 → 1118
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:837 → 865
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:554 → 805
      MYT1; Myelin transcription factor 1

    10. NM_008666.3 → NP_032692.2  myelin transcription factor 1-like protein isoform 2

      See identical proteins and their annotated locations for NP_032692.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the mid-coding region, compared to variant 1, resulting in a shorter protein (isoform 2). Variants 2, 3, 6 and 7 encode the same isoform (2).
      Source sequence(s)
      AK013654, BC094438, BE653129, BQ876229, CB521730, CX240996
      Consensus CDS
      CCDS49041.1
      UniProtKB/TrEMBL
      Q0VGN2
      Related
      ENSMUSP00000151588.2, ENSMUST00000218583.2
      Conserved Domains (3) summary
      COG1196
      Location:1032 → 1184
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:903 → 931
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:620 → 871
      MYT1; Myelin transcription factor 1

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      29578375..29973215
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011243823.4 → XP_011242125.1  myelin transcription factor 1-like protein isoform X1

      See identical proteins and their annotated locations for XP_011242125.1

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      TIGR04211
      Location:1061 → 1139
      SH3_and_anchor; SH3 domain protein
      pfam01530
      Location:905 → 933
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:622 → 873
      MYT1; Myelin transcription factor 1

    2. XM_030246587.2 → XP_030102447.1  myelin transcription factor 1-like protein isoform X4

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:1032 → 1184
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:903 → 931
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:620 → 871
      MYT1; Myelin transcription factor 1

    3. XM_011243819.4 → XP_011242121.1  myelin transcription factor 1-like protein isoform X1

      See identical proteins and their annotated locations for XP_011242121.1

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      TIGR04211
      Location:1061 → 1139
      SH3_and_anchor; SH3 domain protein
      pfam01530
      Location:905 → 933
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:622 → 873
      MYT1; Myelin transcription factor 1

    4. XM_030246582.2 → XP_030102442.1  myelin transcription factor 1-like protein isoform X3

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      TIGR04211
      Location:1059 → 1137
      SH3_and_anchor; SH3 domain protein
      pfam01530
      Location:903 → 931
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:620 → 871
      MYT1; Myelin transcription factor 1

    5. XM_030246588.2 → XP_030102448.1  myelin transcription factor 1-like protein isoform X5

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:1013 → 1167
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:884 → 912
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:601 → 852
      MYT1; Myelin transcription factor 1

    6. XM_036157214.1 → XP_036013107.1  myelin transcription factor 1-like protein isoform X7

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:1011 → 1165
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:882 → 910
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:599 → 850
      MYT1; Myelin transcription factor 1

    7. XM_030246594.2 → XP_030102454.1  myelin transcription factor 1-like protein isoform X16

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:868 → 1022
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:739 → 767
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:456 → 707
      MYT1; Myelin transcription factor 1

    8. XM_030246596.2 → XP_030102456.1  myelin transcription factor 1-like protein isoform X17

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:866 → 1020
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:737 → 765
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:454 → 705
      MYT1; Myelin transcription factor 1

    9. XM_036157213.1 → XP_036013106.1  myelin transcription factor 1-like protein isoform X5

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:1013 → 1167
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:884 → 912
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:601 → 852
      MYT1; Myelin transcription factor 1

    10. XM_030246584.2 → XP_030102444.1  myelin transcription factor 1-like protein isoform X3

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      TIGR04211
      Location:1059 → 1137
      SH3_and_anchor; SH3 domain protein
      pfam01530
      Location:903 → 931
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:620 → 871
      MYT1; Myelin transcription factor 1

    11. XM_030246592.2 → XP_030102452.1  myelin transcription factor 1-like protein isoform X16

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:868 → 1022
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:739 → 767
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:456 → 707
      MYT1; Myelin transcription factor 1

    12. XM_011243820.4 → XP_011242122.1  myelin transcription factor 1-like protein isoform X1

      See identical proteins and their annotated locations for XP_011242122.1

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      TIGR04211
      Location:1061 → 1139
      SH3_and_anchor; SH3 domain protein
      pfam01530
      Location:905 → 933
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:622 → 873
      MYT1; Myelin transcription factor 1

    13. XM_011243818.4 → XP_011242120.1  myelin transcription factor 1-like protein isoform X1

      See identical proteins and their annotated locations for XP_011242120.1

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      TIGR04211
      Location:1061 → 1139
      SH3_and_anchor; SH3 domain protein
      pfam01530
      Location:905 → 933
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:622 → 873
      MYT1; Myelin transcription factor 1

    14. XM_011243833.4 → XP_011242135.1  myelin transcription factor 1-like protein isoform X9

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      TIGR04211
      Location:1061 → 1139
      SH3_and_anchor; SH3 domain protein
      pfam01530
      Location:905 → 933
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:622 → 873
      MYT1; Myelin transcription factor 1

    15. XM_011243827.4 → XP_011242129.1  myelin transcription factor 1-like protein isoform X2

      See identical proteins and their annotated locations for XP_011242129.1

      UniProtKB/Swiss-Prot
      A2RRK5, D3Z1P7, O08996, P97500, Q33DP0, Q8C643, Q8C7L4, Q8CHB4
      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:1034 → 1186
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:905 → 933
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:622 → 873
      MYT1; Myelin transcription factor 1

    16. XM_030246581.2 → XP_030102441.1  myelin transcription factor 1-like protein isoform X3

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      TIGR04211
      Location:1059 → 1137
      SH3_and_anchor; SH3 domain protein
      pfam01530
      Location:903 → 931
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:620 → 871
      MYT1; Myelin transcription factor 1

    17. XM_030246591.2 → XP_030102451.1  myelin transcription factor 1-like protein isoform X11

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      TIGR04211
      Location:1059 → 1137
      SH3_and_anchor; SH3 domain protein
      pfam01530
      Location:903 → 931
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:620 → 871
      MYT1; Myelin transcription factor 1

    18. XM_036157215.1 → XP_036013108.1  myelin transcription factor 1-like protein isoform X13

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:987 → 1141
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:858 → 886
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:575 → 826
      MYT1; Myelin transcription factor 1

    19. XM_017314976.3 → XP_017170465.1  myelin transcription factor 1-like protein isoform X14

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:987 → 1139
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:858 → 886
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:575 → 826
      MYT1; Myelin transcription factor 1

    20. XM_017314980.3 → XP_017170469.1  myelin transcription factor 1-like protein isoform X16

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:868 → 1022
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:739 → 767
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:456 → 707
      MYT1; Myelin transcription factor 1

    21. XM_030246595.2 → XP_030102455.1  myelin transcription factor 1-like protein isoform X17

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:866 → 1020
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:737 → 765
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:454 → 705
      MYT1; Myelin transcription factor 1

    22. XM_011243831.4 → XP_011242133.1  myelin transcription factor 1-like protein isoform X5

      See identical proteins and their annotated locations for XP_011242133.1

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:1013 → 1167
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:884 → 912
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:601 → 852
      MYT1; Myelin transcription factor 1

    23. XM_030246589.2 → XP_030102449.1  myelin transcription factor 1-like protein isoform X6

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:1013 → 1165
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:884 → 912
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:601 → 852
      MYT1; Myelin transcription factor 1

    24. XM_017314971.3 → XP_017170460.1  myelin transcription factor 1-like protein isoform X7

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:1011 → 1165
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:882 → 910
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:599 → 850
      MYT1; Myelin transcription factor 1

    25. XM_017314972.3 → XP_017170461.1  myelin transcription factor 1-like protein isoform X8

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:1011 → 1163
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:882 → 910
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:599 → 850
      MYT1; Myelin transcription factor 1

    26. XM_017314978.3 → XP_017170467.1  myelin transcription factor 1-like protein isoform X15

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:984 → 1118
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:837 → 865
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:554 → 805
      MYT1; Myelin transcription factor 1

    27. XM_011243834.4 → XP_011242136.1  myelin transcription factor 1-like protein isoform X10

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      pfam01530
      Location:905 → 933
      zf-C2HC; Zinc finger, C2HC type
      pfam05667
      Location:893 → 1118
      DUF812; Protein of unknown function (DUF812)
      pfam08474
      Location:622 → 873
      MYT1; Myelin transcription factor 1

    28. XM_017314974.3 → XP_017170463.1  myelin transcription factor 1-like protein isoform X12

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      pfam01530
      Location:903 → 931
      zf-C2HC; Zinc finger, C2HC type
      pfam05667
      Location:891 → 1116
      DUF812; Protein of unknown function (DUF812)
      pfam08474
      Location:620 → 871
      MYT1; Myelin transcription factor 1

    29. XM_036157218.1 → XP_036013111.1  myelin transcription factor 1-like protein isoform X18

      Conserved Domains (2) summary
      pfam01530
      Location:30 → 58
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:622 → 873
      MYT1; Myelin transcription factor 1

    30. XM_036157219.1 → XP_036013112.1  myelin transcription factor 1-like protein isoform X19

      Conserved Domains (2) summary
      pfam01530
      Location:30 → 58
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:620 → 871
      MYT1; Myelin transcription factor 1

    31. XM_011243824.4 → XP_011242126.1  myelin transcription factor 1-like protein isoform X1

      See identical proteins and their annotated locations for XP_011242126.1

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      TIGR04211
      Location:1061 → 1139
      SH3_and_anchor; SH3 domain protein
      pfam01530
      Location:905 → 933
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:622 → 873
      MYT1; Myelin transcription factor 1

    32. XM_030246585.2 → XP_030102445.1  myelin transcription factor 1-like protein isoform X3

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      TIGR04211
      Location:1059 → 1137
      SH3_and_anchor; SH3 domain protein
      pfam01530
      Location:903 → 931
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:620 → 871
      MYT1; Myelin transcription factor 1

    33. XM_036157216.1 → XP_036013109.1  myelin transcription factor 1-like protein isoform X16

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:868 → 1022
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:739 → 767
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:456 → 707
      MYT1; Myelin transcription factor 1

    34. XM_036157217.1 → XP_036013110.1  myelin transcription factor 1-like protein isoform X17

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:866 → 1020
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:737 → 765
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:454 → 705
      MYT1; Myelin transcription factor 1

    35. XM_030246576.2 → XP_030102436.1  myelin transcription factor 1-like protein isoform X1

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      TIGR04211
      Location:1061 → 1139
      SH3_and_anchor; SH3 domain protein
      pfam01530
      Location:905 → 933
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:622 → 873
      MYT1; Myelin transcription factor 1

    36. XM_036157211.1 → XP_036013104.1  myelin transcription factor 1-like protein isoform X2

      UniProtKB/Swiss-Prot
      A2RRK5, D3Z1P7, O08996, P97500, Q33DP0, Q8C643, Q8C7L4, Q8CHB4
      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:1034 → 1186
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:905 → 933
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:622 → 873
      MYT1; Myelin transcription factor 1

    37. XM_030246583.2 → XP_030102443.1  myelin transcription factor 1-like protein isoform X3

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      TIGR04211
      Location:1059 → 1137
      SH3_and_anchor; SH3 domain protein
      pfam01530
      Location:903 → 931
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:620 → 871
      MYT1; Myelin transcription factor 1

    38. XM_030246593.2 → XP_030102453.1  myelin transcription factor 1-like protein isoform X16

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:868 → 1022
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:739 → 767
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:456 → 707
      MYT1; Myelin transcription factor 1

    39. XM_011243832.4 → XP_011242134.1  myelin transcription factor 1-like protein isoform X5

      See identical proteins and their annotated locations for XP_011242134.1

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:1013 → 1167
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:884 → 912
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:601 → 852
      MYT1; Myelin transcription factor 1

    40. XM_030246590.2 → XP_030102450.1  myelin transcription factor 1-like protein isoform X7

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:1011 → 1165
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:882 → 910
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:599 → 850
      MYT1; Myelin transcription factor 1

    41. XM_036157212.1 → XP_036013105.1  myelin transcription factor 1-like protein isoform X4

      UniProtKB/TrEMBL
      Q0VGN2
      Conserved Domains (3) summary
      COG1196
      Location:1032 → 1184
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam01530
      Location:903 → 931
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:620 → 871
      MYT1; Myelin transcription factor 1
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P97500.3 GenPept UniProtKB/Swiss-Prot:P97500

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