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    Ubtd2 ubiquitin domain containing 2 [ Mus musculus (house mouse) ]

    Gene ID: 327900, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Ubtd2provided by MGI
    Official Full Name
    ubiquitin domain containing 2provided by MGI
    Primary source
    MGI:MGI:2444752
    See related
    Ensembl:ENSMUSG00000044949 AllianceGenome:MGI:2444752
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4930571L24; 9630054F20Rik
    Summary
    Predicted to be located in cytoplasm. Orthologous to human UBTD2 (ubiquitin domain containing 2). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in limb E14.5 (RPKM 18.8), CNS E11.5 (RPKM 16.7) and 22 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Ubtd2 in Genome Data Viewer
    Location:
    11 A4; 11 18.94 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (32405370..32468709)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (32455370..32518709)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene SH3 and PX domains 2B Neighboring gene predicted gene, 51948 Neighboring gene STARR-positive B cell enhancer ABC_E11474 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:32442680-32442833 Neighboring gene EF-hand calcium binding domain 9 Neighboring gene serine/threonine kinase 10

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    2. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ubiquitin domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001361561.1 → NP_001348490.1  ubiquitin domain-containing protein 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL662780, AL669844
      Conserved Domains (2) summary
      cd01794
      Location:75 → 144
      DC_UbP_C; dendritic cell derived ubiquitin-like protein
      pfam16455
      Location:24 → 53
      UBD; Ubiquitin-binding domain

    2. NM_173784.4 → NP_776145.2  ubiquitin domain-containing protein 2 isoform 1

      See identical proteins and their annotated locations for NP_776145.2

      Status: VALIDATED

      Source sequence(s)
      AK076953, BC057026
      Consensus CDS
      CCDS24527.1
      UniProtKB/Swiss-Prot
      A2AAY6, Q6PGH0, Q8C5Y1
      Related
      ENSMUSP00000056765.5, ENSMUST00000051053.5
      Conserved Domains (3) summary
      cd01794
      Location:154 → 223
      DC_UbP_C; dendritic cell derived ubiquitin-like protein
      smart00213
      Location:153 → 223
      UBQ; Ubiquitin homologues
      pfam16455
      Location:28 → 132
      UBD; Ubiquitin-binding domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      32405370..32468709
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6PGH0.1 GenPept UniProtKB/Swiss-Prot:Q6PGH0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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