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    Zfp867 zinc finger protein 867 [ Mus musculus (house mouse) ]

    Gene ID: 237775, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Zfp867provided by MGI
    Official Full Name
    zinc finger protein 867provided by MGI
    Primary source
    MGI:MGI:2681848
    See related
    Ensembl:ENSMUSG00000054519 AllianceGenome:MGI:2681848
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF136 (zinc finger protein 136) and ZNF627 (zinc finger protein 627). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in CNS E18 (RPKM 3.6), CNS E14 (RPKM 3.2) and 23 other tissues See more
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    Genomic context

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    See Zfp867 in Genome Data Viewer
    Location:
    11 B1.3; 11 37.71 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (59352023..59363353, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (59461197..59472527, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_29623 Neighboring gene serine protease 38 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:59198075-59198323 Neighboring gene predicted gene 15755 Neighboring gene synaptosomal-associated protein, 47 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:59263537-59263646 Neighboring gene STARR-seq mESC enhancer starr_29624 Neighboring gene jumonji domain containing 4 Neighboring gene ariadne homolog 2 pseudogene Neighboring gene zinc finger with KRAB and SCAN domains 17 Neighboring gene RIKEN cDNA 4933439C10 gene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    2. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
    3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC60963

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 867
    Names
    zinc finger protein LOC237775

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178417.3 → NP_848504.2  zinc finger protein 867

      Status: VALIDATED

      Source sequence(s)
      AK132062, AL592522
      Consensus CDS
      CCDS24769.1
      UniProtKB/TrEMBL
      E9Q2M4
      Related
      ENSMUSP00000050746.8, ENSMUST00000057799.8
      Conserved Domains (5) summary
      smart00349
      Location:12 → 52
      KRAB; krueppel associated box
      COG5048
      Location:119 → 431
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:207 → 227
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 51
      KRAB; KRAB box
      pfam13465
      Location:247 → 272
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      59352023..59363353 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011248984.3 → XP_011247286.1  zinc finger protein 867 isoform X1

      Conserved Domains (3) summary
      sd00017
      Location:207 → 227
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:11 → 51
      KRAB; KRAB box
      pfam13465
      Location:247 → 272
      zf-H2C2_2; Zinc-finger double domain

    2. XM_030245963.1 → XP_030101823.1  zinc finger protein 867 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:14 → 326
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:102 → 122
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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