Serf1 small EDRK-rich factor 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Serf1provided by MGI
Official Full Name: small EDRK-rich factor 1provided by MGI
Primary source: MGI:MGI:1337114
See related: Ensembl:ENSMUSG00000021643 AllianceGenome:MGI:1337114
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 4F5; m4F5; Msmac1
Summary: Predicted to be involved in amyloid fibril formation and protein destabilization. Predicted to be located in cytosol and nucleus. Predicted to be part of protein-containing complex. Is expressed in several structures, including central nervous system and retina. Orthologous to human SERF1A (small EDRK-rich factor 1A) and SERF1B (small EDRK-rich factor 1B). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in testis adult (RPKM 237.6), CNS E18 (RPKM 77.7) and 4 other tissues See more
Orthologs: human all
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Genomic context

Location:: 13 D1; 13 52.98 cM

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	13	NC_000079.7 (100244563..100250741)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	13	NC_000079.6 (100108019..100114233)

Chromosome 13 - NC_000079.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (1)

General gene information

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Markers

D13Die11 (e-PCR), detects polymorphism
- UniSTS:141900

D13Die13 (e-PCR), detects polymorphism
- UniSTS:141902

D13Die22 (e-PCR), detects polymorphism
- UniSTS:141908

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in amyloid fibril formation	IEA Inferred from Electronic Annotation more info
involved_in biological_process	ND No biological Data available more info
involved_in protein destabilization	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
part_of protein-containing complex	IEA Inferred from Electronic Annotation more info
part_of protein-containing complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: small EDRK-rich factor 1

Names: modifier of spinal muscular atrophy candidate 1; protein 4F5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.