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    Fam149a family with sequence similarity 149, member A [ Mus musculus (house mouse) ]

    Gene ID: 212326, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Fam149aprovided by MGI
    Official Full Name
    family with sequence similarity 149, member Aprovided by MGI
    Primary source
    MGI:MGI:2387177
    See related
    Ensembl:ENSMUSG00000070044 AllianceGenome:MGI:2387177
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mKIAA4166
    Summary
    Is expressed in renal calyx. Orthologous to human FAM149A (family with sequence similarity 149 member A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in kidney adult (RPKM 6.4), bladder adult (RPKM 4.2) and 26 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Fam149a in Genome Data Viewer
    Location:
    8 B1.1; 8 25.25 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (45789752..45835328, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (45336715..45382291, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 30504 Neighboring gene kallikrein B, plasma 1 Neighboring gene cytochrome P450, family 4, subfamily v, polypeptide 3 Neighboring gene STARR-seq mESC enhancer starr_21371 Neighboring gene toll-like receptor 3 Neighboring gene sorbin and SH3 domain containing 2 Neighboring gene predicted gene, 30759

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (4) 

    General gene information

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    Markers

    Homology

    Clone Names

    • KIAA4166, MGC40851

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM149A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153535.2 → NP_705763.1  protein FAM149A

      See identical proteins and their annotated locations for NP_705763.1

      Status: VALIDATED

      Source sequence(s)
      AK140440, AK141607, BB183041
      Consensus CDS
      CCDS22277.1
      UniProtKB/Swiss-Prot
      Q8CFV2
      Related
      ENSMUSP00000091245.7, ENSMUST00000093526.13
      Conserved Domains (1) summary
      pfam12516
      Location:306 → 369
      DUF3719; Protein of unknown function (DUF3719)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      45789752..45835328 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011242184.2 → XP_011240486.1  protein FAM149A isoform X1

      Conserved Domains (2) summary
      PRK12323
      Location:56 → 282
      PRK12323; DNA polymerase III subunit gamma/tau
      pfam12516
      Location:306 → 370
      DUF3719; Protein of unknown function (DUF3719)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8CFV2.1 GenPept UniProtKB/Swiss-Prot:Q8CFV2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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