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    FAM181B family with sequence similarity 181 member B [ Homo sapiens (human) ]

    Gene ID: 220382, updated on 10-Dec-2024

    Summary

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    Official Symbol
    FAM181Bprovided by HGNC
    Official Full Name
    family with sequence similarity 181 member Bprovided by HGNC
    Primary source
    HGNC:HGNC:28512
    See related
    Ensembl:ENSG00000182103 AllianceGenome:HGNC:28512
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Orthologs
    mouse all
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    Genomic context

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    See FAM181B in Genome Data Viewer
    Location:
    11q14.1
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (82729940..82733864, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (82666398..82670322, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (82440982..82444906, complement)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105369410 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:82364504-82365004 Neighboring gene MPRA-validated peak1371 silencer Neighboring gene Sharpr-MPRA regulatory region 11396 Neighboring gene ribosomal protein S28 pseudogene 7 Neighboring gene long intergenic non-protein coding RNA 2734 Neighboring gene RBMX pseudogene 3 Neighboring gene eukaryotic translation initiation factor 2 subunit 2 beta pseudogene 6 Neighboring gene prolylcarboxypeptidase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of the Fam181 gene family during mouse development reveals distinct strain-specific expression patterns, suggesting a role in nervous system development and function. Marks M, et al. Gene, 2016 Jan 10. PMID 26407640
    2. A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition. Benslimane Y, et al. Aging Cell, 2021 Apr. PMID 33660365, Free PMC Article
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC33846

    General protein information

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    Preferred Names
    protein FAM181B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175885.4 → NP_787081.2  protein FAM181B

      See identical proteins and their annotated locations for NP_787081.2

      Status: VALIDATED

      Source sequence(s)
      AP002796, BC039262, BE857184, BE858471
      Consensus CDS
      CCDS31648.1
      UniProtKB/Swiss-Prot
      A6NEQ2, B2RWP1
      Related
      ENSP00000365295.2, ENST00000329203.5
      Conserved Domains (1) summary
      pfam15238
      Location:63 → 235
      FAM181; FAM181

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      82729940..82733864 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      82666398..82670322 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_175891.2: Suppressed sequence

      Description
      NM_175891.2: This RefSeq record was removed by NCBI staff. Contact [email protected] for further information.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A6NEQ2.1 GenPept UniProtKB/Swiss-Prot:A6NEQ2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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