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    Utp23 UTP23 small subunit processome component [ Mus musculus (house mouse) ]

    Gene ID: 78581, updated on 9-Dec-2024

    Summary

    Official Symbol
    Utp23provided by MGI
    Official Full Name
    UTP23 small subunit processome componentprovided by MGI
    Primary source
    MGI:MGI:1925831
    See related
    Ensembl:ENSMUSG00000022313 AllianceGenome:MGI:1925831
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700010I21Rik; D530033C11Rik
    Summary
    Predicted to enable mRNA 3'-UTR binding activity; mRNA 5'-UTR binding activity; and small ribosomal subunit rRNA binding activity. Acts upstream of or within endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma. Orthologous to human UTP23 (UTP23 small subunit processome component). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 3.1), testis adult (RPKM 2.8) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Utp23 in Genome Data Viewer
    Location:
    15 C; 15 19.49 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (51740837..51748018)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (51877441..51884622)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41320 Neighboring gene eukaryotic translation initiation factor 3, subunit H Neighboring gene STARR-seq mESC enhancer starr_38653 Neighboring gene STARR-positive B cell enhancer ABC_E4132 Neighboring gene STARR-positive B cell enhancer ABC_E5475 Neighboring gene predicted gene, 34678 Neighboring gene predicted gene, 48923 Neighboring gene STARR-seq mESC enhancer starr_38655 Neighboring gene RAD21 cohesin complex component Neighboring gene STARR-seq mESC enhancer starr_38657 Neighboring gene predicted gene, 52217

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables mRNA 3'-UTR binding  
    enables mRNA 3'-UTR binding  
    enables mRNA 5'-UTR binding  
    enables mRNA 5'-UTR binding  
    enables small ribosomal subunit rRNA binding  
    Component Evidence Code Pubs
    is_active_in nucleolus  
    located_in nucleolus  
    part_of small-subunit processome  
    part_of small-subunit processome  

    General protein information

    Preferred Names
    rRNA-processing protein UTP23 homolog
    Names
    UTP23, small subunit (SSU) processome component, homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_030132.5NP_084408.1  rRNA-processing protein UTP23 homolog

      See identical proteins and their annotated locations for NP_084408.1

      Status: VALIDATED

      Source sequence(s)
      AK134445, BB338032, BC046791, CK334116
      Consensus CDS
      CCDS27462.1
      UniProtKB/Swiss-Prot
      Q8BY14, Q9CX11
      Related
      ENSMUSP00000119261.3, ENSMUST00000137116.3
      Conserved Domains (1) summary
      cd09866
      Location:2148
      PIN_Fcf1-Utp23-H; PIN domain of rRNA-processing protein Fcf1- and Utp23-like homologs found in eukaryotes except fungi

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      51740837..51748018
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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