U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    NIT1 Nit1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854642, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    NIT1
    Official Full Name
    Nit1p
    Primary source
    SGD:S000001426
    Locus tag
    YIL164C
    See related
    AllianceGenome:SGD:S000001426; FungiDB:YIL164C; VEuPathDB:YIL164C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable nitrilase activity. [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See NIT1 in Genome Data Viewer
    Location:
    chromosome: IX
    Exon count:
    1
    Sequence:
    Chromosome: IX; NC_001141.2 (34087..34686, complement)

    Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene Soa1p Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene beta-fructofuranosidase SUC2

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001141.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Effect of 21 different nitrogen sources on global gene expression in the yeast Saccharomyces cerevisiae. Godard P, et al. Mol Cell Biol, 2007 Apr. PMID 17308034, Free PMC Article
    2. Tup1-Ssn6 and Swi-Snf remodelling activities influence long-range chromatin organization upstream of the yeast SUC2 gene. Fleming AB, et al. Nucleic Acids Res, 2007. PMID 17704134, Free PMC Article
    3. Sequencing and comparison of yeast species to identify genes and regulatory elements. Kellis M, et al. Nature, 2003 May 15. PMID 12748633
    4. Crystal structure of the worm NitFhit Rosetta Stone protein reveals a Nit tetramer binding two Fhit dimers. Pace HC, et al. Curr Biol, 2000 Jul 27-Aug 10. PMID 10959838
    5. Exploring Quantitative Yeast Phenomics with Single-Cell Analysis of DNA Damage Foci. Styles EB, et al. Cell Syst, 2016 Sep 28. PMID 27617677, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydro-lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nitrilase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nitrilase activity ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Nit1p
    NP_012102.1
    • Nitrilase; member of the nitrilase branch of the nitrilase superfamily; in closely related species and other S. cerevisiae strain backgrounds YIL164C and adjacent ORF, YIL165C, likely constitute a single ORF encoding a nitrilase gene

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001141.2 Reference assembly

      Range
      34087..34686 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179512.1 → NP_012102.1  TPA: Nit1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012102.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VVC3, P40447, Q05729, Q6Q5A1
      UniProtKB/TrEMBL
      B5VKF0, G2WFY7, N1P9A2
      Conserved Domains (1) summary
      cl11424
      Location:4 → 198
      nitrilase; Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P40447.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools