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    putative haloacid dehalogenase-like hydrolase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854299, updated on 9-Dec-2024

    Summary

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    Official Full Name
    putative haloacid dehalogenase-like hydrolase
    Primary source
    SGD:S000005657
    Locus tag
    YOR131C
    See related
    AllianceGenome:SGD:S000005657; FungiDB:YOR131C; VEuPathDB:YOR131C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables pyridoxal phosphatase activity. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (572182..572838, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Ort1p Neighboring gene tRNA-Asp Neighboring gene retromer subunit VPS17 Neighboring gene elongation factor 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome-wide analysis of the effects of heat shock on a Saccharomyces cerevisiae mutant with a constitutively activated cAMP-dependent pathway. Jones DL, et al. Comp Funct Genomics, 2004. PMID 18629174, Free PMC Article
    2. Functional Diversity of Haloacid Dehalogenase Superfamily Phosphatases from Saccharomyces cerevisiae: BIOCHEMICAL, STRUCTURAL, AND EVOLUTIONARY INSIGHTS. Kuznetsova E, et al. J Biol Chem, 2015 Jul 24. PMID 26071590, Free PMC Article
    3. Synchronized assembly of the oxidative phosphorylation system controls mitochondrial respiration in yeast. Moretti-Horten DN, et al. Dev Cell, 2024 Apr 22. PMID 38508182
    4. Mechanisms of cell cycle control revealed by a systematic and quantitative overexpression screen in S. cerevisiae. Niu W, et al. PLoS Genet, 2008 Jul 11. PMID 18617996, Free PMC Article
    5. Purified Smc5/6 Complex Exhibits DNA Substrate Recognition and Compaction. Gutierrez-Escribano P, et al. Mol Cell, 2020 Dec 17. PMID 33301732, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pyridoxal phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative haloacid dehalogenase-like hydrolase
    NP_014774.1
    • Putative haloacid dehalogenase-like hydrolase; non-essential gene; overexpression causes a cell cycle delay or arrest; protein abundance increases in response to DNA replication stress

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      572182..572838 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183550.1 → NP_014774.1  TPA: putative haloacid dehalogenase-like hydrolase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014774.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W2I9, Q12486
      UniProtKB/TrEMBL
      A6ZNX8, B3LJH3, B5VS21, C7GMK8, C8ZI93, N1NWM3
      Conserved Domains (1) summary
      COG0546
      Location:10 → 213
      Gph; Phosphoglycolate phosphatase, HAD superfamily [Energy production and conversion]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12486.1

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