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    TMA23 Tma23p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855311, updated on 9-Dec-2024

    Summary

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    Official Symbol
    TMA23
    Official Full Name
    Tma23p
    Primary source
    SGD:S000004882
    Locus tag
    YMR269W
    See related
    AllianceGenome:SGD:S000004882; FungiDB:YMR269W; VEuPathDB:YMR269W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    YMR268W-A
    Summary
    Involved in ribosomal small subunit biogenesis. Located in nucleolus. Orthologous to human GPATCH4 (G-patch domain containing 4 (gene/pseudogene)). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See TMA23 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (804456..805091)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene inorganic diphosphatase PPA2 Neighboring gene U6 snRNP complex subunit PRP24 Neighboring gene Rrn9p Neighboring gene orotate phosphoribosyltransferase URA10

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mutations in the nucleolar proteins Tma23 and Nop6 suppress the malfunction of the Nep1 protein. Buchhaupt M, et al. FEMS Yeast Res, 2007 Sep. PMID 17425675
    2. Constructing gene co-expression networks and predicting functions of unknown genes by random matrix theory. Luo F, et al. BMC Bioinformatics, 2007 Aug 14. PMID 17697349, Free PMC Article
    3. Multiple TORC1-associated proteins regulate nitrogen starvation-dependent cellular differentiation in Saccharomyces cerevisiae. Laxman S, et al. PLoS One, 2011. PMID 22043304, Free PMC Article
    4. Hydrogen peroxide sensitivity connects the activity of COX5A and NPR3 to the regulation of YAP1 expression. Takallou S, et al. FASEB J, 2024 Mar 15. PMID 38416461
    5. Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Fleischer TC, et al. Genes Dev, 2006 May 15. PMID 16702403, Free PMC Article

    See all (42) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. the identification of tma23 and nop6 mutations as recessive suppressors of a nep1(ts) mutant allele and the nep1 deletion as well
      Title: Mutations in the nucleolar proteins Tma23 and Nop6 suppress the malfunction of the Nep1 protein.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in ribosomal small subunit biogenesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleolus HDA PubMed 
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Tma23p
    NP_013996.2
    • Nucleolar protein implicated in ribosome biogenesis; deletion extends chronological lifespan

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      804456..805091
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182776.1 → NP_013996.2  TPA: Tma23p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013996.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W095, Q03525, Q7Z870
      UniProtKB/TrEMBL
      B3LMF6, B5VQ33, C7GR85, C8ZFD5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q03525.2

    Gene LinkOut

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