Ndufv3 NADH:ubiquinone oxidoreductase subunit V3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ndufv3provided by RGD
Official Full Name: NADH:ubiquinone oxidoreductase subunit V3provided by RGD
Primary source: RGD:621020
See related: EnsemblRapid:ENSRNOG00000001182 AllianceGenome:RGD:621020
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Mipp65; Ndufv3l
Summary: Predicted to be involved in mitochondrial ATP synthesis coupled electron transport. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex I. Orthologous to human NDUFV3 (NADH:ubiquinone oxidoreductase subunit V3). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Heart (RPKM 795.9), Kidney (RPKM 482.3) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 20p12

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	20	NC_086038.1 (9613786..9622941)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	20	NC_051355.1 (9612462..9621622)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	20	NC_005119.4 (10265826..10275298)

Chromosome 20 - NC_086038.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

we describe characterization of the complexes I purified from five rat tissues and from a rat hepatoma cell line. We identify a~50kDa isoform of subunit NDUFV3, for which the canonical isoform is only ~10kDa in size.
Title: Subunit NDUFV3 is present in two distinct isoforms in mammalian complex I.
OBAP is mainly produced by mitochondria of parietal cells in the upper and lower parts of the gastric epithelium.
Title: Spatial distribution of osteoblast activating peptide in the rat stomach.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH129486 (e-PCR)
- UniSTS:212791

RH139157 (e-PCR)
- UniSTS:221243

RH129888 (e-PCR)
- UniSTS:213176

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in mitochondrial ATP synthesis coupled electron transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrial ATP synthesis coupled electron transport	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in mitochondrial inner membrane	ISO Inferred from Sequence Orthology more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info
part_of respiratory chain complex I	IBA Inferred from Biological aspect of Ancestor more info
part_of respiratory chain complex I	IEA Inferred from Electronic Annotation more info
part_of respiratory chain complex I	ISO Inferred from Sequence Orthology more info
part_of respiratory chain complex I	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial

Names: CI-9kD; NADH dehydrogenase (ubiquinone) flavoprotein 3; NADH dehydrogenase (ubiquinone) flavoprotein 3-like; NADH-ubiquinone oxidoreductase 9 kDa subunit; complex I-9kD

NP_001094481.1

EC 7.1.1.2

NP_072129.2

EC 7.1.1.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.