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    Chpt1 choline phosphotransferase 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362866, updated on 27-Nov-2024

    Summary

    Official Symbol
    Chpt1provided by RGD
    Official Full Name
    choline phosphotransferase 1provided by RGD
    Primary source
    RGD:1359283
    See related
    EnsemblRapid:ENSRNOG00000058271 AllianceGenome:RGD:1359283
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable diacylglycerol cholinephosphotransferase activity. Predicted to be involved in platelet activating factor biosynthetic process. Predicted to act upstream of or within phosphatidylcholine biosynthetic process. Predicted to be active in Golgi membrane and endoplasmic reticulum membrane. Orthologous to human CHPT1 (choline phosphotransferase 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Kidney (RPKM 494.2), Heart (RPKM 384.6) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Chpt1 in Genome Data Viewer
    Location:
    7q13
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (24753880..24802529, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (22866455..22915111, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (29019518..29070928, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene proline-rich basic protein 1, pseudogene 1 Neighboring gene DNA-damage regulated autophagy modulator 1 Neighboring gene N-acetylglucosamine-1-phosphate transferase subunits alpha and beta Neighboring gene synaptonemal complex protein 3 Neighboring gene uncharacterized LOC102554140 Neighboring gene myosin binding protein C1 Neighboring gene uncharacterized LOC120093549

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC95241

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    cholinephosphotransferase 1
    Names
    cholinephosphotransferase 1 alpha
    diacylglycerol cholinephosphotransferase 1
    NP_001381255.1
    XP_006241292.1
    XP_038935364.1
    XP_038935367.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001394326.1NP_001381255.1  cholinephosphotransferase 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000007
      UniProtKB/Swiss-Prot
      Q66H21
      Related
      ENSRNOP00000102864.1, ENSRNOT00000167914.1
      Conserved Domains (1) summary
      cl00453
      Location:25337
      CDP-OH_P_transf; CDP-alcohol phosphatidyltransferase

    RNA

    1. NR_172095.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000007

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      24753880..24802529 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039079436.2XP_038935364.1  cholinephosphotransferase 1 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZZB6
      Related
      ENSRNOP00000106967.1, ENSRNOT00000162025.1
      Conserved Domains (1) summary
      cl00453
      Location:25337
      CDP-OH_P_transf; CDP-alcohol phosphatidyltransferase
    2. XM_006241230.4XP_006241292.1  cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8I6GI18
      Related
      ENSRNOP00000084340.2, ENSRNOT00000094926.2
      Conserved Domains (1) summary
      cl00453
      Location:25337
      CDP-OH_P_transf; CDP-alcohol phosphatidyltransferase
    3. XM_039079439.2XP_038935367.1  cholinephosphotransferase 1 isoform X3

      Conserved Domains (1) summary
      cl00453
      Location:25207
      CDP-OH_P_transf; CDP-alcohol phosphatidyltransferase