Nr3c1 nuclear receptor subfamily 3, group C, member 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Nr3c1provided by MGI
Official Full Name: nuclear receptor subfamily 3, group C, member 1provided by MGI
Primary source: MGI:MGI:95824
See related: Ensembl:ENSMUSG00000024431 AllianceGenome:MGI:95824
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: GR; Grl1; Grl-1
Summary: Enables several functions, including identical protein binding activity; nuclear glucocorticoid receptor activity; and promoter-specific chromatin binding activity. Involved in several processes, including glial cell differentiation; nuclear receptor-mediated glucocorticoid signaling pathway; and positive regulation of miRNA transcription. Acts upstream of or within several processes, including maternal behavior; regulation of primary metabolic process; and response to cortisol. Located in cytosol; membrane; and nucleus. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and leg muscle. Used to study primary hyperaldosteronism. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; anorexia nervosa; cocaine abuse; heroin dependence; and lung disease (multiple). Orthologous to human NR3C1 (nuclear receptor subfamily 3 group C member 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Ubiquitous expression in bladder adult (RPKM 11.2), subcutaneous fat pad adult (RPKM 8.1) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 18 B3; 18 21.09 cM

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	18	NC_000084.7 (39543598..39652485, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	18	NC_000084.6 (39410545..39519421, complement)

Chromosome 18 - NC_000084.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

USP10-mediated deubiquitination of NR3C1 regulates bone homeostasis by controlling CST3 expression.
Title: USP10-mediated deubiquitination of NR3C1 regulates bone homeostasis by controlling CST3 expression.
The Regulation of Frontal Cortex Cholesterol Metabolism Abnormalities by NR3C1/NRIP1/NR1H2 Is Involved in the Occurrence of Stress-Induced Depression.
Title: The Regulation of Frontal Cortex Cholesterol Metabolism Abnormalities by NR3C1/NRIP1/NR1H2 Is Involved in the Occurrence of Stress-Induced Depression.
ClassIIb histone deacetylase participates in perioperative neurocognitive disorders in elderly mice via HSP90/GR signaling pathway.
Title: ClassIIb histone deacetylase participates in perioperative neurocognitive disorders in elderly mice via HSP90/GR signaling pathway.
LncRNA Gm15232 Promotes Lipogenesis in Aging Mice Through the miR-192-3p/GCR Pathway.
Title: LncRNA Gm15232 Promotes Lipogenesis in Aging Mice Through the miR-192-3p/GCR Pathway.
The glucocorticoid receptor acts locally to protect dystrophic muscle and heart during disease.
Title: The glucocorticoid receptor acts locally to protect dystrophic muscle and heart during disease.
A cell cycle regulator, E2F2, and glucocorticoid receptor cooperatively transactivate the bovine alphaherpesvirus 1 immediate early transcription unit 1 promoter.
Title: A cell cycle regulator, E2F2, and glucocorticoid receptor cooperatively transactivate the bovine alphaherpesvirus 1 immediate early transcription unit 1 promoter.
Cardiac GR Mediates the Diurnal Rhythm in Ventricular Arrhythmia Susceptibility.
Title: Cardiac GR Mediates the Diurnal Rhythm in Ventricular Arrhythmia Susceptibility.
Impaired glucocorticoid receptor function attenuates herpes simplex virus 1 production during explant-induced reactivation from latency in female mice.
Title: Impaired glucocorticoid receptor function attenuates herpes simplex virus 1 production during explant-induced reactivation from latency in female mice.
The glucocorticoid receptor in skeletal health and disease: insights from targeted knockout mice.
Title: The glucocorticoid receptor in skeletal health and disease: insights from targeted knockout mice.
Glucocorticoid Receptor (GR) Activation Is Associated with Increased cAMP/PKA Signaling in Castration-Resistant Prostate Cancer.
Title: Glucocorticoid Receptor (GR) Activation Is Associated with Increased cAMP/PKA Signaling in Castration-Resistant Prostate Cancer.

Submit: New GeneRIF Correction See all GeneRIFs (285)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (6)
Gene trapped (1) 1 citation
Targeted (19) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

NR3C1 (e-PCR)
- UniSTS:504891

X04435 (e-PCR)
- UniSTS:125783

Nr3c1 (e-PCR), detects polymorphism
- UniSTS:461926

Nr3c1 (e-PCR), detects polymorphism
- UniSTS:527462

Nr3c1 (e-PCR), detects polymorphism
- UniSTS:143264

D18Mit17 (e-PCR), detects polymorphism
- UniSTS:128190

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription activator activity, RNA polymerase II-specific	ISO Inferred from Sequence Orthology more info
enables DNA-binding transcription factor activity	ISO Inferred from Sequence Orthology more info
enables DNA-binding transcription repressor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO Inferred from Sequence Orthology more info
enables Hsp70 protein binding	ISO Inferred from Sequence Orthology more info
enables Hsp90 protein binding	IEA Inferred from Electronic Annotation more info
enables Hsp90 protein binding	ISO Inferred from Sequence Orthology more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO Inferred from Sequence Orthology more info
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO Inferred from Sequence Orthology more info
enables TBP-class protein binding	IEA Inferred from Electronic Annotation more info
enables TBP-class protein binding	ISO Inferred from Sequence Orthology more info
enables chromatin binding	ISO Inferred from Sequence Orthology more info
enables core promoter sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info
enables core promoter sequence-specific DNA binding	ISO Inferred from Sequence Orthology more info
enables double-stranded DNA binding	ISO Inferred from Sequence Orthology more info
enables estrogen response element binding	IBA Inferred from Biological aspect of Ancestor more info
enables heat shock protein binding	ISO Inferred from Sequence Orthology more info
enables hormone binding	ISO Inferred from Sequence Orthology more info
enables identical protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables nuclear glucocorticoid receptor activity	IDA Inferred from Direct Assay more info	PubMed
enables nuclear receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables nuclear receptor activity	ISO Inferred from Sequence Orthology more info
enables nuclear receptor activity	ISS Inferred from Sequence or Structural Similarity more info
enables promoter-specific chromatin binding	IDA Inferred from Direct Assay more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein kinase binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein kinase binding	ISO Inferred from Sequence Orthology more info
enables protein-containing complex binding	ISO Inferred from Sequence Orthology more info
enables receptor tyrosine kinase binding	ISO Inferred from Sequence Orthology more info
enables sequence-specific DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables sequence-specific DNA binding	ISO Inferred from Sequence Orthology more info
enables sequence-specific double-stranded DNA binding	ISO Inferred from Sequence Orthology more info
enables steroid binding	ISO Inferred from Sequence Orthology more info
enables steroid binding	ISS Inferred from Sequence or Structural Similarity more info
enables steroid hormone binding	ISO Inferred from Sequence Orthology more info
enables steroid hormone binding	ISS Inferred from Sequence or Structural Similarity more info
enables transcription coactivator activity	ISO Inferred from Sequence Orthology more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within adrenal gland development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in astrocyte differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cellular response to dexamethasone stimulus	IEA Inferred from Electronic Annotation more info
involved_in cellular response to dexamethasone stimulus	ISO Inferred from Sequence Orthology more info
involved_in cellular response to glucocorticoid stimulus	ISO Inferred from Sequence Orthology more info
involved_in cellular response to steroid hormone stimulus	ISO Inferred from Sequence Orthology more info
involved_in cellular response to transforming growth factor beta stimulus	IEA Inferred from Electronic Annotation more info
involved_in cellular response to transforming growth factor beta stimulus	ISO Inferred from Sequence Orthology more info
involved_in chromatin organization	IEA Inferred from Electronic Annotation more info
involved_in chromatin remodeling	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within gene expression	IDA Inferred from Direct Assay more info	PubMed
involved_in gene expression	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in glucocorticoid mediated signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within glucocorticoid metabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within mammary gland duct morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within maternal behavior	IGI Inferred from Genetic Interaction more info	PubMed
involved_in microglia differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in motor behavior	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of DNA-templated transcription	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of apoptotic process	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of synaptic plasticity	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of vascular permeability	ISO Inferred from Sequence Orthology more info
involved_in neuroinflammatory response	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in nuclear receptor-mediated corticosteroid signaling pathway	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within nuclear receptor-mediated glucocorticoid signaling pathway	IDA Inferred from Direct Assay more info	PubMed
involved_in nuclear receptor-mediated glucocorticoid signaling pathway	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within nuclear receptor-mediated glucocorticoid signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in nuclear receptor-mediated steroid hormone signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of cell growth involved in cardiac muscle cell development	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of dendritic spine development	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of glucocorticoid receptor signaling pathway	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of glutamate secretion	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of miRNA transcription	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of miRNA transcription	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of neuron apoptotic process	IGI Inferred from Genetic Interaction more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of transcription by RNA polymerase II	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within regulation of DNA-templated transcription	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of DNA-templated transcription	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of DNA-templated transcription	ISO Inferred from Sequence Orthology more info
involved_in regulation of cell population proliferation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within regulation of glucocorticoid biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of gluconeogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of glucose metabolic process	ISO Inferred from Sequence Orthology more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in response to arsenic-containing substance	ISO Inferred from Sequence Orthology more info
involved_in response to corticosterone	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within response to cortisol	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within response to wounding	IDA Inferred from Direct Assay more info	PubMed
involved_in synaptic transmission, glutamatergic	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in transcription initiation-coupled chromatin remodeling	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in centrosome	IEA Inferred from Electronic Annotation more info
located_in chromatin	IBA Inferred from Biological aspect of Ancestor more info
located_in chromosome	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in dendritic spine	ISO Inferred from Sequence Orthology more info
is_active_in glutamatergic synapse	ISO Inferred from Sequence Orthology more info
located_in intracellular anatomical structure	IDA Inferred from Direct Assay more info	PubMed
located_in membrane	IDA Inferred from Direct Assay more info	PubMed
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
located_in nuclear speck	ISO Inferred from Sequence Orthology more info
located_in nuclear speck	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	TAS Traceable Author Statement more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
is_active_in nucleus	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
is_active_in postsynaptic density, intracellular component	ISO Inferred from Sequence Orthology more info
part_of protein-containing complex	IEA Inferred from Electronic Annotation more info
part_of protein-containing complex	ISO Inferred from Sequence Orthology more info
located_in spindle	IEA Inferred from Electronic Annotation more info
located_in synapse	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: glucocorticoid receptor

Names: glucocorticoid receptor 1; glucocorticoid receptor subtype P

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001361209.1 → NP_001348138.1 glucocorticoid receptor

Status: VALIDATED

Source sequence(s)

AC007995, AC124417

Consensus CDS

CCDS37791.1

UniProtKB/Swiss-Prot

E0ZPU5, E9PUR6, E9PYV1, P06537, Q06VW2, Q3U126, Q3U2M7, Q61628, Q61629

Related

ENSMUSP00000111229.2, ENSMUST00000115567.8

Conserved Domains (3) summary

cd07076
Location:546 → 792

NR_LBD_GR; Ligand binding domain of the glucocorticoid receptor, a member of the nuclear receptor superfamily

cd07172
Location:433 → 510

NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers

pfam02155
Location:27 → 418

GCR; Glucocorticoid receptor
NM_001361210.1 → NP_001348139.1 glucocorticoid receptor

Status: VALIDATED

Source sequence(s)

AC007995, AC124417

Consensus CDS

CCDS37791.1

UniProtKB/Swiss-Prot

E0ZPU5, E9PUR6, E9PYV1, P06537, Q06VW2, Q3U126, Q3U2M7, Q61628, Q61629

Related

ENSMUSP00000111233.2, ENSMUST00000115571.8

Conserved Domains (3) summary

cd07076
Location:546 → 792

NR_LBD_GR; Ligand binding domain of the glucocorticoid receptor, a member of the nuclear receptor superfamily

cd07172
Location:433 → 510

NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers

pfam02155
Location:27 → 418

GCR; Glucocorticoid receptor
NM_001361211.1 → NP_001348140.1 glucocorticoid receptor

Status: VALIDATED

Source sequence(s)

AC007995, AC124417

Consensus CDS

CCDS37791.1

UniProtKB/Swiss-Prot

E0ZPU5, E9PUR6, E9PYV1, P06537, Q06VW2, Q3U126, Q3U2M7, Q61628, Q61629

Conserved Domains (3) summary

cd07076
Location:546 → 792

NR_LBD_GR; Ligand binding domain of the glucocorticoid receptor, a member of the nuclear receptor superfamily

cd07172
Location:433 → 510

NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers

pfam02155
Location:27 → 418

GCR; Glucocorticoid receptor
NM_001361212.1 → NP_001348141.1 glucocorticoid receptor

Status: VALIDATED

Source sequence(s)

AC007995, AC124417

Consensus CDS

CCDS37791.1

UniProtKB/Swiss-Prot

E0ZPU5, E9PUR6, E9PYV1, P06537, Q06VW2, Q3U126, Q3U2M7, Q61628, Q61629

Conserved Domains (3) summary

cd07076
Location:546 → 792

NR_LBD_GR; Ligand binding domain of the glucocorticoid receptor, a member of the nuclear receptor superfamily

cd07172
Location:433 → 510

NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers

pfam02155
Location:27 → 418

GCR; Glucocorticoid receptor
NM_008173.4 → NP_032199.3 glucocorticoid receptor

See identical proteins and their annotated locations for NP_032199.3

Status: VALIDATED

Source sequence(s)

AC007995, AC124417

Consensus CDS

CCDS37791.1

UniProtKB/Swiss-Prot

E0ZPU5, E9PUR6, E9PYV1, P06537, Q06VW2, Q3U126, Q3U2M7, Q61628, Q61629

Conserved Domains (3) summary

cd07076
Location:546 → 792

NR_LBD_GR; Ligand binding domain of the glucocorticoid receptor, a member of the nuclear receptor superfamily

cd07172
Location:433 → 510

NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers

pfam02155
Location:27 → 418

GCR; Glucocorticoid receptor

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000084.7 Reference GRCm39 C57BL/6J

Range

39543598..39652485 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006525658.3 → XP_006525721.1 glucocorticoid receptor isoform X1

See identical proteins and their annotated locations for XP_006525721.1

UniProtKB/TrEMBL

E9PYV1

Conserved Domains (3) summary

cd07076
Location:547 → 793

NR_LBD_GR; Ligand binding domain of the glucocorticoid receptor, a member of the nuclear receptor superfamily

cd07172
Location:433 → 511

NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers

pfam02155
Location:27 → 418

GCR; Glucocorticoid receptor
XM_006525662.3 → XP_006525725.1 glucocorticoid receptor isoform X1

See identical proteins and their annotated locations for XP_006525725.1

UniProtKB/TrEMBL

E9PYV1

Conserved Domains (3) summary

cd07076
Location:547 → 793

NR_LBD_GR; Ligand binding domain of the glucocorticoid receptor, a member of the nuclear receptor superfamily

cd07172
Location:433 → 511

NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers

pfam02155
Location:27 → 418

GCR; Glucocorticoid receptor
XM_030250339.2 → XP_030106199.1 glucocorticoid receptor isoform X2

UniProtKB/Swiss-Prot

E0ZPU5, E9PUR6, E9PYV1, P06537, Q06VW2, Q3U126, Q3U2M7, Q61628, Q61629

Conserved Domains (3) summary

cd07076
Location:546 → 792

NR_LBD_GR; Ligand binding domain of the glucocorticoid receptor, a member of the nuclear receptor superfamily

cd07172
Location:433 → 510

NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers

pfam02155
Location:27 → 418

GCR; Glucocorticoid receptor
XM_006525664.3 → XP_006525727.1 glucocorticoid receptor isoform X1

See identical proteins and their annotated locations for XP_006525727.1

UniProtKB/TrEMBL

E9PYV1

Conserved Domains (3) summary

cd07076
Location:547 → 793

NR_LBD_GR; Ligand binding domain of the glucocorticoid receptor, a member of the nuclear receptor superfamily

cd07172
Location:433 → 511

NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers

pfam02155
Location:27 → 418

GCR; Glucocorticoid receptor
XM_006525659.5 → XP_006525722.1 glucocorticoid receptor isoform X1

See identical proteins and their annotated locations for XP_006525722.1

UniProtKB/TrEMBL

E9PYV1

Conserved Domains (3) summary

cd07076
Location:547 → 793

NR_LBD_GR; Ligand binding domain of the glucocorticoid receptor, a member of the nuclear receptor superfamily

cd07172
Location:433 → 511

NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers

pfam02155
Location:27 → 418

GCR; Glucocorticoid receptor
XM_036160990.1 → XP_036016883.1 glucocorticoid receptor isoform X2

UniProtKB/Swiss-Prot

E0ZPU5, E9PUR6, E9PYV1, P06537, Q06VW2, Q3U126, Q3U2M7, Q61628, Q61629

Conserved Domains (3) summary

cd07076
Location:546 → 792

NR_LBD_GR; Ligand binding domain of the glucocorticoid receptor, a member of the nuclear receptor superfamily

cd07172
Location:433 → 510

NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers

pfam02155
Location:27 → 418

GCR; Glucocorticoid receptor
XM_030250338.2 → XP_030106198.1 glucocorticoid receptor isoform X2

UniProtKB/Swiss-Prot

E0ZPU5, E9PUR6, E9PYV1, P06537, Q06VW2, Q3U126, Q3U2M7, Q61628, Q61629

Related

ENSMUSP00000025300.7, ENSMUST00000025300.13

Conserved Domains (3) summary

cd07076
Location:546 → 792

NR_LBD_GR; Ligand binding domain of the glucocorticoid receptor, a member of the nuclear receptor superfamily

cd07172
Location:433 → 510

NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers

pfam02155
Location:27 → 418

GCR; Glucocorticoid receptor
XM_006525661.4 → XP_006525724.1 glucocorticoid receptor isoform X1

See identical proteins and their annotated locations for XP_006525724.1

UniProtKB/TrEMBL

E9PYV1

Conserved Domains (3) summary

cd07076
Location:547 → 793

NR_LBD_GR; Ligand binding domain of the glucocorticoid receptor, a member of the nuclear receptor superfamily

cd07172
Location:433 → 511

NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers

pfam02155
Location:27 → 418

GCR; Glucocorticoid receptor
XM_006525663.5 → XP_006525726.1 glucocorticoid receptor isoform X1

See identical proteins and their annotated locations for XP_006525726.1

UniProtKB/TrEMBL

E9PYV1

Conserved Domains (3) summary

cd07076
Location:547 → 793

NR_LBD_GR; Ligand binding domain of the glucocorticoid receptor, a member of the nuclear receptor superfamily

cd07172
Location:433 → 511

NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers

pfam02155
Location:27 → 418

GCR; Glucocorticoid receptor
XM_006525665.5 → XP_006525728.1 glucocorticoid receptor isoform X1

See identical proteins and their annotated locations for XP_006525728.1

UniProtKB/TrEMBL

E9PYV1

Related

ENSMUSP00000095199.3, ENSMUST00000097592.9

Conserved Domains (3) summary

cd07076
Location:547 → 793

NR_LBD_GR; Ligand binding domain of the glucocorticoid receptor, a member of the nuclear receptor superfamily

cd07172
Location:433 → 511

NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers

pfam02155
Location:27 → 418

GCR; Glucocorticoid receptor
XM_006525660.4 → XP_006525723.1 glucocorticoid receptor isoform X1

See identical proteins and their annotated locations for XP_006525723.1

UniProtKB/TrEMBL

E9PYV1

Conserved Domains (3) summary

cd07076
Location:547 → 793

NR_LBD_GR; Ligand binding domain of the glucocorticoid receptor, a member of the nuclear receptor superfamily

cd07172
Location:433 → 511

NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers

pfam02155
Location:27 → 418

GCR; Glucocorticoid receptor