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    Gm10033 predicted gene 10033 [ Mus musculus (house mouse) ]

    Gene ID: 378466, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Gm10033provided by MGI
    Official Full Name
    predicted gene 10033provided by MGI
    Primary source
    MGI:MGI:3642803
    See related
    Ensembl:ENSMUSG00000110444 AllianceGenome:MGI:3642803
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm10311; 9330175B10Rik; E230024E03Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in cerebellum adult (RPKM 1.7), bladder adult (RPKM 1.4) and 21 other tissues See more
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    Genomic context

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    See Gm10033 in Genome Data Viewer
    Location:
    8 B3.3; 8
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (69821180..69848196, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (69368528..69395544, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E2263 Neighboring gene STARR-seq mESC enhancer starr_21728 Neighboring gene zinc finger protein 781A Neighboring gene STARR-seq mESC enhancer starr_21730 Neighboring gene STARR-positive B cell enhancer mm9_chr8:71852567-71852867 Neighboring gene eukaryotic translation initiation factor 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_21735 Neighboring gene POTE ankyrin domain family member 3C Neighboring gene STARR-positive B cell enhancer mm9_chr8:71994362-71994663 Neighboring gene POTE ankyrin domain family member 3D

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    2. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC378466

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001374599.1 → NP_001361528.1  uncharacterized protein LOC378466 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC117621, AC162797
      UniProtKB/TrEMBL
      A0A6I8MX06
      Related
      ENSMUSP00000159337.2, ENSMUST00000239456.2
      Conserved Domains (3) summary
      COG5048
      Location:469 → 845
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:529 → 549
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:40 → 80
      KRAB; KRAB box

    2. NM_001374600.1 → NP_001361529.1  uncharacterized protein LOC378466 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC117621, AC162797
      UniProtKB/TrEMBL
      A0A6I8MX21
      Related
      ENSMUSP00000159375.2, ENSMUST00000072427.7
      Conserved Domains (3) summary
      COG5048
      Location:433 → 809
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:493 → 513
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:4 → 44
      KRAB; KRAB box

    RNA

    1. NR_038043.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) is the longer transcript with multiple exons.
      Source sequence(s)
      AC117621, AC162797

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      69821180..69848196 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_194351.1: Suppressed sequence

      Description
      NM_194351.1: This RefSeq was permanently suppressed because it is now thought that this gene does not encode a protein.

    2. NR_038044.1: Suppressed sequence

      Description
      NR_038044.1: This RefSeq was removed because currently there is not sufficient data to support this transcript.
    Nucleotide Protein Strain
    Heading Accession and Version

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