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    F41E6.5 FMN hydroxy acid dehydrogenase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 179241, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F41E6.5
    Official Full Name
    FMN hydroxy acid dehydrogenase domain-containing protein
    Primary source
    WormBase:WBGene00018286
    Locus tag
    CELE_F41E6.5
    See related
    AllianceGenome:WB:WBGene00018286
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable (S)-2-hydroxy-acid oxidase activity. Predicted to be involved in fatty acid alpha-oxidation. Predicted to be located in peroxisome. Predicted to be active in peroxisomal matrix. Is expressed in intestine and pharynx. Orthologous to several human genes including HAO1 (hydroxyacid oxidase 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F41E6.5 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    6
    Sequence:
    Chromosome: V; NC_003283.11 (8603480..8605181)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Sushi domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene Charged multivesicular body protein 5 Neighboring gene Serine/threonine-protein phosphatase 4 regulatory subunit 3-like central domain-containing protein Neighboring gene Fungus-Induced Protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables (S)-2-hydroxy-acid oxidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables FMN binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in peroxisomal matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in peroxisome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    FMN hydroxy acid dehydrogenase domain-containing protein
    NP_001122941.1
    • Confirmed by transcript evidence
    NP_001359850.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      8603480..8605181
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001129469.3 → NP_001122941.1  FMN hydroxy acid dehydrogenase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122941.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B1GRK5
      Conserved Domains (1) summary
      pfam01070
      Location:18 → 361
      FMN_dh; FMN-dependent dehydrogenase

    2. NM_001373065.3 → NP_001359850.1  FMN hydroxy acid dehydrogenase domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      O16457
      Conserved Domains (1) summary
      pfam01070
      Location:18 → 287
      FMN_dh; FMN-dependent dehydrogenase
    Nucleotide Protein
    Heading Accession and Version

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