U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    nhr-109 NR LBD domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 173780, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    nhr-109
    Official Full Name
    NR LBD domain-containing protein
    Primary source
    WormBase:WBGene00003699
    Locus tag
    CELE_T12C9.5
    See related
    AllianceGenome:WB:WBGene00003699
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See nhr-109 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    5
    Sequence:
    Chromosome: II; NC_003280.10 (4433395..4435169)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene DDB1- and CUL4-associated factor 13 Neighboring gene HEAT repeat-containing protein 1 homolog Neighboring gene Nuclear Hormone Receptor family Neighboring gene Nuclear hormone receptor family member nhr-16

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
    2. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article
    3. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    NR LBD domain-containing protein
    NP_001022341.1
    • Confirmed by transcript evidence
    NP_001368017.1
    • Confirmed by transcript evidence
    NP_001380054.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      4433395..4435169
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001393051.1 → NP_001380054.1  NR LBD domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86PJ1, Q9U371
      Conserved Domains (2) summary
      pfam00104
      Location:77 → 286
      Hormone_recep; Ligand-binding domain of nuclear hormone receptor
      cl02596
      Location:1 → 17
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

    2. NM_001381389.1 → NP_001368017.1  NR LBD domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L0L6, Q86PJ1
      Conserved Domains (2) summary
      smart00399
      Location:12 → 80
      ZnF_C4; c4 zinc finger in nuclear hormone receptors
      pfam00104
      Location:140 → 349
      Hormone_recep; Ligand-binding domain of nuclear hormone receptor

    3. NM_001027170.5 → NP_001022341.1  NR LBD domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022341.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JP54, Q86PJ1
      Conserved Domains (2) summary
      smart00430
      Location:116 → 286
      HOLI; Ligand binding domain of hormone receptors
      cl02596
      Location:11 → 35
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools