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    ent-7 Equilibrative Nucleoside Transporter (ENT) Family [ Caenorhabditis elegans ]

    Gene ID: 177862, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ent-7
    Official Full Name
    Equilibrative Nucleoside Transporter (ENT) Family
    Primary source
    WormBase:WBGene00009686
    Locus tag
    CELE_F44D12.9
    See related
    AllianceGenome:WB:WBGene00009686
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable nucleoside transmembrane transporter activity. Predicted to be involved in nucleoside transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in histiocytosis-lymphadenopathy plus syndrome. Orthologous to several human genes including SLC29A3 (solute carrier family 29 member 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ent-7 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    10
    Sequence:
    Chromosome: IV; NC_003282.8 (10017425..10021290)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene PDZ domain-containing protein Neighboring gene DUF281 domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Phosphotriesterase-related protein Neighboring gene MSP domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans. LeGendre JB, et al. J Biol Chem, 2013 Jan 25. PMID 23195953, Free PMC Article
    2. Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain. Dube F, et al. PLoS One, 2023. PMID 37141255, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables nucleoside transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables nucleoside transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in nucleoside transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in nucleoside transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Equilibrative Nucleoside Transporter (ENT) Family
    NP_001255452.1
    • Confirmed by transcript evidence
    NP_001367263.1
    • Confirmed by transcript evidence
    NP_001379100.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      10017425..10021290
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001380428.1 → NP_001367263.1  Equilibrative Nucleoside Transporter (ENT) Family [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1B6S1
      Conserved Domains (1) summary
      cl15430
      Location:56 → 439
      Nucleoside_tran; Nucleoside transporter

    2. NM_001392380.1 → NP_001379100.1  Equilibrative Nucleoside Transporter (ENT) Family [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20396
      Conserved Domains (1) summary
      cl15430
      Location:44 → 427
      Nucleoside_tran; Nucleoside transporter

    3. NM_001268523.3 → NP_001255452.1  Equilibrative Nucleoside Transporter (ENT) Family [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255452.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1B6S0
      Conserved Domains (1) summary
      cl15430
      Location:1 → 139
      Nucleoside_tran; Nucleoside transporter

    RNA

    1. NR_131591.1 RNA Sequence

      Status: REVIEWED

    Nucleotide Protein
    Heading Accession and Version

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