efhd-1 EF-hand domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: efhd-1
Official Full Name: EF-hand domain-containing protein
Primary source: WormBase:WBGene00012980
Locus tag: CELE_Y48B6A.6
See related: AllianceGenome:WB:WBGene00012980
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable calcium ion binding activity. Is expressed in body wall musculature; nervous system; and pharynx. Orthologous to several human genes including EFHD1 (EF-hand domain family member D1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See efhd-1 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 9

Sequence:: Chromosome: II; NC_003280.10 (14180259..14189917)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Y48B6A.6 (e-PCR)
- UniSTS:321742

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables calcium ion binding	IBA Inferred from Biological aspect of Ancestor more info
enables calcium ion binding	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: EF-hand domain-containing protein

NP_001122657.1

Confirmed by transcript evidence

NP_496961.2

Confirmed by transcript evidence

NP_871966.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

14180259..14189917

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_064560.7 → NP_496961.2 EF-hand domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_496961.2

Status: REVIEWED

UniProtKB/TrEMBL

Q9U2A6

Conserved Domains (1) summary

cd00051
Location:545 → 602

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
NM_182166.7 → NP_871966.2 EF-hand domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_871966.2

Status: REVIEWED

UniProtKB/TrEMBL

Q8I0Z7

Conserved Domains (1) summary

cd00051
Location:61 → 118

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
NM_001129185.5 → NP_001122657.1 EF-hand domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001122657.1

Status: REVIEWED

UniProtKB/TrEMBL

A8XMZ5

Conserved Domains (1) summary

cd00051
Location:37 → 94

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...