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    sel-15 Protein kinase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 175225, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sel-15
    Official Full Name
    Protein kinase domain-containing protein
    Primary source
    WormBase:WBGene00016030
    Locus tag
    CELE_C24A1.3
    See related
    AllianceGenome:WB:WBGene00016030
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein kinase activity. Predicted to be involved in protein phosphorylation. Is expressed in nervous system. Orthologous to human FPGT-TNNI3K (FPGT-TNNI3K readthrough) and TNNI3K (TNNI3 interacting kinase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See sel-15 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    11
    Sequence:
    Chromosome: III; NC_003281.10 (692509..696472, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor kinase 2 Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein Neighboring gene ETS domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A pathway for phagosome maturation during engulfment of apoptotic cells. Kinchen JM, et al. Nat Cell Biol, 2008 May. PMID 18425118, Free PMC Article
    2. Genomic overview of protein kinases. Manning G. WormBook, 2005 Dec 13. PMID 18050405, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Protein kinase domain-containing protein
    NP_001366799.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      692509..696472 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001381697.1 → NP_001366799.1  Protein kinase domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A679L8N8
      Conserved Domains (4) summary
      PHA03095
      Location:128 → 388
      PHA03095; ankyrin-like protein; Provisional
      COG0666
      Location:3 → 217
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd14064
      Location:522 → 780
      PKc_TNNI3K; Catalytic domain of the Dual-specificity protein kinase, TNNI3-interacting kinase
      sd00045
      Location:285 → 318
      ANK; ANK repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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