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    T10C6.6 Major facilitator superfamily (MFS) profile domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 180070, updated on 9-Dec-2024

    Summary

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    Official Symbol
    T10C6.6
    Official Full Name
    Major facilitator superfamily (MFS) profile domain-containing protein
    Primary source
    WormBase:WBGene00011688
    Locus tag
    CELE_T10C6.6
    See related
    AllianceGenome:WB:WBGene00011688
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Located in plasma membrane. Orthologous to human SLC37A3 (solute carrier family 37 member 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See T10C6.6 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    6
    Sequence:
    Chromosome: V; NC_003283.11 (16024326..16027459)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene 7TM GPCR serpentine receptor class x (Srx) domain-containing protein Neighboring gene Spliceosome-associated protein CWC15 homolog Neighboring gene F-box domain-containing protein Neighboring gene pseudo Neighboring gene FBA_2 domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
    2. A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding. Lenfant N, et al. BMC Genomics, 2010 Nov 26. PMID 21110867, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    Major facilitator superfamily (MFS) profile domain-containing protein
    NP_001366951.1
    • Confirmed by transcript evidence
    NP_001368108.1
    • Confirmed by transcript evidence
    NP_001368109.1
    • Confirmed by transcript evidence
    NP_001368110.1
    • Confirmed by transcript evidence
    NP_001368111.1
    • Confirmed by transcript evidence
    NP_507025.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      16024326..16027459
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_074624.7 → NP_507025.1  Major facilitator superfamily (MFS) profile domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_507025.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O62376
      Conserved Domains (1) summary
      cd17342
      Location:9 → 428
      MFS_SLC37A3; Solute carrier family 37 member 3 of the Major Facilitator Superfamily of transporters

    2. NM_001380836.1 → NP_001368109.1  Major facilitator superfamily (MFS) profile domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2FLL7
      Conserved Domains (1) summary
      cd17342
      Location:9 → 437
      MFS_SLC37A3; Solute carrier family 37 member 3 of the Major Facilitator Superfamily of transporters

    3. NM_001380839.2 → NP_001368110.1  Major facilitator superfamily (MFS) profile domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2FLL8
      Conserved Domains (1) summary
      cl28910
      Location:1 → 368
      MFS; Major Facilitator Superfamily

    4. NM_001380840.1 → NP_001366951.1  Major facilitator superfamily (MFS) profile domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U372
      Conserved Domains (1) summary
      cl28910
      Location:1 → 359
      MFS; Major Facilitator Superfamily

    5. NM_001380837.1 → NP_001368111.1  Major facilitator superfamily (MFS) profile domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2FLL9
      Conserved Domains (1) summary
      cd17342
      Location:5 → 433
      MFS_SLC37A3; Solute carrier family 37 member 3 of the Major Facilitator Superfamily of transporters

    6. NM_001380838.1 → NP_001368108.1  Major facilitator superfamily (MFS) profile domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2FLL6
      Conserved Domains (1) summary
      cd17342
      Location:5 → 424
      MFS_SLC37A3; Solute carrier family 37 member 3 of the Major Facilitator Superfamily of transporters
    Nucleotide Protein
    Heading Accession and Version

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