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    gip-1 Gamma-tubulin complex component [ Caenorhabditis elegans ]

    Gene ID: 175355, updated on 9-Dec-2024

    Summary

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    Official Symbol
    gip-1
    Official Full Name
    Gamma-tubulin complex component
    Primary source
    WormBase:WBGene00001589
    Locus tag
    CELE_H04J21.3
    See related
    AllianceGenome:WB:WBGene00001589
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable gamma-tubulin binding activity. Predicted to contribute to microtubule minus-end binding activity. Predicted to be involved in meiotic cell cycle; microtubule cytoskeleton organization; and mitotic cell cycle. Predicted to be located in cytoplasm; membrane; and microtubule cytoskeleton. Predicted to be part of gamma-tubulin complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See gip-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    14
    Sequence:
    Chromosome: III; NC_003281.10 (2347591..2362056)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene PPM-type phosphatase domain-containing protein Neighboring gene PHD finger-like domain-containing protein 5A Neighboring gene Serpentine Receptor, class D (Delta) Neighboring gene Ubiquitin-like domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Tissue-specific degradation of essential centrosome components reveals distinct microtubule populations at microtubule organizing centers. Sallee MD, et al. PLoS Biol, 2018 Aug. PMID 30080857, Free PMC Article
    2. The kinetically dominant assembly pathway for centrosomal asters in Caenorhabditis elegans is gamma-tubulin dependent. Hannak E, et al. J Cell Biol, 2002 May 13. PMID 12011109, Free PMC Article
    3. Aurora-A kinase is required for centrosome maturation in Caenorhabditis elegans. Hannak E, et al. J Cell Biol, 2001 Dec 24. PMID 11748251, Free PMC Article
    4. Katanin controls mitotic and meiotic spindle length. McNally K, et al. J Cell Biol, 2006 Dec 18. PMID 17178907, Free PMC Article
    5. PTRN-1 (CAMSAP) and NOCA-2 (NINEIN) are required for microtubule polarity in Caenorhabditis elegans dendrites. He L, et al. PLoS Biol, 2022 Nov. PMID 36395330, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables gamma-tubulin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables gamma-tubulin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    contributes_to microtubule minus-end binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic microtubule organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in meiotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in microtubule cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in microtubule nucleation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in microtubule nucleation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in spindle assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of gamma-tubulin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in microtubule organizing center IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in spindle pole IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Gamma-tubulin complex component
    NP_001022632.1
    • Confirmed by transcript evidence
    NP_497540.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      2347591..2362056
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001027461.4 → NP_001022632.1  Gamma-tubulin complex component [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022632.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O61208, Q8MTJ4
      Conserved Domains (1) summary
      pfam04130
      Location:305 → 636
      Spc97_Spc98; Spc97 / Spc98 family

    2. NM_065139.8 → NP_497540.3  Gamma-tubulin complex component [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497540.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8ITY3
      Conserved Domains (1) summary
      pfam04130
      Location:305 → 636
      Spc97_Spc98; Spc97 / Spc98 family
    Nucleotide Protein
    Heading Accession and Version

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