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    Y53F4B.14 Protein PET100 homolog, mitochondrial;TPX2 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 175157, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y53F4B.14
    Official Full Name
    Protein PET100 homolog, mitochondrial;TPX2 domain-containing protein
    Primary source
    WormBase:WBGene00013161
    Locus tag
    CELE_Y53F4B.14
    See related
    AllianceGenome:WB:WBGene00013161
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable unfolded protein binding activity. Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be located in membrane and mitochondrion. Predicted to be active in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 12. Orthologous to human PET100 (PET100 cytochrome c oxidase chaperone). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y53F4B.14 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003280.10 (15037991..15039297)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 Neighboring gene ncRNA Neighboring gene TRIP4/RQT4 C2HC5-type zinc finger domain-containing protein Neighboring gene ncRNA Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables unfolded protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial cytochrome c oxidase assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial cytochrome c oxidase assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrial inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Protein PET100 homolog, mitochondrial;TPX2 domain-containing protein
    NP_001254461.1
    • Partially confirmed by transcript evidence
    NP_001254462.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      15037991..15039297
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001267532.2 → NP_001254461.1  Protein PET100 homolog, mitochondrial [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001254461.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9NAA4
      Conserved Domains (1) summary
      pfam09803
      Location:1 → 59
      DUF2346; Uncharacterized conserved protein (DUF2346)

    2. NM_001267533.3 → NP_001254462.1  TPX2 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001254462.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H8ESH7
      Conserved Domains (1) summary
      pfam09803
      Location:2 → 47
      DUF2346; Uncharacterized conserved protein (DUF2346)
    Nucleotide Protein
    Heading Accession and Version

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