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    pigg-1 GPI ethanolamine phosphate transferase 2 [ Caenorhabditis elegans ]

    Gene ID: 174377, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pigg-1
    Official Full Name
    GPI ethanolamine phosphate transferase 2
    Primary source
    WormBase:WBGene00009204
    Locus tag
    CELE_F28C6.4
    See related
    AllianceGenome:WB:WBGene00009204
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable CP2 mannose-ethanolamine phosphotransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human PIGG (phosphatidylinositol glycan anchor biosynthesis class G (EMM blood group)). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See pigg-1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    11
    Sequence:
    Chromosome: II; NC_003280.10 (8596275..8600265, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ADP-ribosylation factor-like protein 1 Neighboring gene GDP/GTP exchange factor Sec2 N-terminal domain-containing protein Neighboring gene Transcription factor aptf-4 Neighboring gene Transcription factor AP-2 C-terminal domain-containing protein Neighboring gene Amelotin Neighboring gene Cleavage stimulation factor 50 kDa subunit Neighboring gene ncRNA Neighboring gene Large ribosomal subunit protein uL24

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables CP2 mannose-ethanolamine phosphotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables mannose-ethanolamine phosphotransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in GPI anchor biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in GPI anchor biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    GPI ethanolamine phosphate transferase 2
    NP_001022123.1
    • Confirmed by transcript evidence
    NP_001367076.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      8596275..8600265 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001026952.4 → NP_001022123.1  GPI ethanolamine phosphate transferase 2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022123.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19870
      Conserved Domains (1) summary
      cd16024
      Location:54 → 328
      GPI_EPT_2; GPI ethanolamine phosphate transferase 2; PIG-G

    2. NM_001381530.2 → NP_001367076.1  GPI ethanolamine phosphate transferase 2 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JM05
      Conserved Domains (1) summary
      cd16024
      Location:54 → 328
      GPI_EPT_2; GPI ethanolamine phosphate transferase 2; PIG-G
    Nucleotide Protein
    Heading Accession and Version

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