C47E12.2 ADP/ATP translocase [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: C47E12.2
Official Full Name: ADP/ATP translocase
Primary source: WormBase:WBGene00008147
Locus tag: CELE_C47E12.2
See related: AllianceGenome:WB:WBGene00008147
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable ATP:ADP antiporter activity. Predicted to be involved in negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. Predicted to be located in mitochondrial inner membrane. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See C47E12.2 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 7

Sequence:: Chromosome: IV; NC_003282.8 (10001974..10003502, complement)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C47E12.1 (e-PCR)
- UniSTS:321288

C47E12.2 (e-PCR)
- UniSTS:307350

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables ATP:ADP antiporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in mitochondrial ADP transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in mitochondrial ATP transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ADP/ATP translocase

NP_001379107.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

10001974..10003502 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001392378.1 → NP_001379107.1 ADP/ATP translocase [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

Q18683

Conserved Domains (1) summary

PTZ00169
Location:21 → 306

PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional