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    T28H10.1 L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase [ Caenorhabditis elegans ]

    Gene ID: 189061, updated on 9-Dec-2024

    Summary

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    Official Symbol
    T28H10.1
    Official Full Name
    L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
    Primary source
    WormBase:WBGene00012142
    Locus tag
    CELE_T28H10.1
    See related
    AllianceGenome:WB:WBGene00012142
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable holo-[acyl-carrier-protein] synthase activity. Predicted to be involved in lysine biosynthetic process via aminoadipic acid. Predicted to be active in cytosol. Orthologous to human AASDHPPT (aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See T28H10.1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (12503794..12505146)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene C2H2-type domain-containing protein Neighboring gene PWI domain-containing protein;RRM domain-containing protein Neighboring gene Neuropeptide-Like Protein Neighboring gene ncRNA Neighboring gene ShKT domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables holo-[acyl-carrier-protein] synthase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables holo-[acyl-carrier-protein] synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in lysine biosynthetic process via aminoadipic acid IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
    NP_001380253.1
    • Confirmed by transcript evidence
    NP_506135.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      12503794..12505146
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001392627.1 → NP_001380253.1  L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A486WWX1
      Conserved Domains (1) summary
      COG2091
      Location:35 → 203
      Sfp; Phosphopantetheinyl transferase [Coenzyme transport and metabolism]

    2. NM_073734.4 → NP_506135.2  L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_506135.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22856
      Conserved Domains (1) summary
      COG2091
      Location:35 → 206
      Sfp; Phosphopantetheinyl transferase [Coenzyme transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version

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