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    ugt-17 glucuronosyltransferase [ Caenorhabditis elegans ]

    Gene ID: 179406, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ugt-17
    Official Full Name
    glucuronosyltransferase
    Primary source
    WormBase:WBGene00007422
    Locus tag
    CELE_C08B6.1
    See related
    AllianceGenome:WB:WBGene00007422
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Orthologous to several human genes including UGT2A1 (UDP glucuronosyltransferase family 2 member A1 complex locus); UGT2A3 (UDP glucuronosyltransferase family 2 member A3); and UGT2B10 (UDP glucuronosyltransferase family 2 member B10). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ugt-17 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    7
    Sequence:
    Chromosome: V; NC_003283.11 (10102592..10104964, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Purple acid phosphatase Neighboring gene DUF19 domain-containing protein;PIR Superfamily Protein Neighboring gene Uncharacterized protein Neighboring gene Glycosyltransferase family 92 protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Alternative chaperone machinery may compensate for calreticulin/calnexin deficiency in Caenorhabditis elegans. Lee W, et al. Proteomics, 2006 Feb. PMID 16404716
    2. UDP-glycosyltransferase family in Haemonchus contortus: Phylogenetic analysis, constitutive expression, sex-differences and resistance-related differences. Matoušková P, et al. Int J Parasitol Drugs Drug Resist, 2018 Dec. PMID 30293057, Free PMC Article
    3. Distinct patterns of gene and protein expression elicited by organophosphorus pesticides in Caenorhabditis elegans. Lewis JA, et al. BMC Genomics, 2009 Apr 29. PMID 19402892, Free PMC Article
    4. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables UDP-glycosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables UDP-glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glucuronosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    glucuronosyltransferase
    NP_001122841.1
    • Confirmed by transcript evidence
    NP_505597.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      10102592..10104964 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073196.8 → NP_505597.2  glucuronosyltransferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_505597.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q17813
      Conserved Domains (1) summary
      cd03784
      Location:21 → 469
      GT1_Gtf-like; UDP-glycosyltransferases and similar proteins

    2. NM_001129369.6 → NP_001122841.1  glucuronosyltransferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122841.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A5JYT6
      Conserved Domains (2) summary
      PHA03392
      Location:1 → 513
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
      pfam00201
      Location:22 → 538
      UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase
    Nucleotide Protein
    Heading Accession and Version

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