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    M04G7.2 Protein-tyrosine phosphatase;Tyrosine-protein phosphatase [ Caenorhabditis elegans ]

    Gene ID: 187449, updated on 27-Dec-2024

    Summary

    Official Symbol
    M04G7.2
    Official Full Name
    Protein-tyrosine phosphatase;Tyrosine-protein phosphatase
    Primary source
    WormBase:WBGene00019773
    Locus tag
    CELE_M04G7.2
    See related
    AllianceGenome:WB:WBGene00019773
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in axon guidance and signal transduction. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See M04G7.2 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    8
    Sequence:
    Chromosome: IV; NC_003282.8 (458017..461029, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Secreted protein Neighboring gene ShKT domain-containing protein Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

    Interactions

    General gene information

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in axon guidance  
    involved_in protein dephosphorylation  
    involved_in signal transduction  

    General protein information

    Preferred Names
    Protein-tyrosine phosphatase;Tyrosine-protein phosphatase
    NP_001294337.1
    • Partially confirmed by transcript evidence
    NP_499934.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      458017..461029 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067533.5NP_499934.1  Protein-tyrosine phosphatase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499934.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O44180
      Conserved Domains (2) summary
      smart00194
      Location:266520
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cd00047
      Location:292520
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    2. NM_001307408.3NP_001294337.1  Tyrosine-protein phosphatase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294337.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PBF5
      Conserved Domains (2) summary
      smart00194
      Location:264518
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cd00047
      Location:290518
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
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