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    grpE heat shock protein GrpE [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 881766, updated on 24-Aug-2024

    Summary

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    Gene symbol
    grpE
    Gene description
    heat shock protein GrpE
    Locus tag
    PA4762
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (5349201..5349761, complement)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene molecular chaperone DnaJ Neighboring gene molecular chaperone DnaK Neighboring gene DNA repair protein RecN Neighboring gene ferric uptake regulation protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Escherichia coli grpE gene codes for heat shock protein B25.3, essential for both lambda DNA replication at all temperatures and host growth at high temperature. Ang D, et al. J Bacteriol, 1986 Jul. PMID 2424889, Free PMC Article
    2. Escherichia coli heat shock gene mutants are defective in proteolysis. Straus DB, et al. Genes Dev, 1988 Dec. PMID 3149251
    3. Protein folding in the cytoplasm of Escherichia coli: requirements for the DnaK-DnaJ-GrpE and GroEL-GroES molecular chaperone machines. Thomas JG, et al. Mol Microbiol, 1996 Sep. PMID 8898387
    4. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    5. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to heat ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within protein folding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within proteolysis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    heat shock protein GrpE
    NP_253450.1
    • Product name confidence: class 2 (High similarity to functionally studied protein)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      5349201..5349761 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_253450.1 heat shock protein GrpE [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_253450.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A3M5ETE7
      Conserved Domains (2) summary
      PRK14151
      Location:1 → 174
      PRK14151; heat shock protein GrpE; Provisional
      cd00446
      Location:35 → 85
      GrpE; 2-helical coiled coil [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9HV42.1

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