U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    popB translocator protein PopB [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 880867, updated on 24-Aug-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    popB
    Gene description
    translocator protein PopB
    Locus tag
    PA1708
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_002516.2 (1853665..1854837)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene type III secretion regulator Neighboring gene type III secretion protein PcrV Neighboring gene regulatory protein PcrH Neighboring gene translocator outer membrane protein PopD Neighboring gene exoenzyme S synthesis protein ExsC

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Type 3 Secretion Translocators Spontaneously Assemble a Hexadecameric Transmembrane Complex. Romano FB, et al. J Biol Chem, 2016 Mar 18. PMID 26786106, Free PMC Article
    2. Binding mode analysis of a major T3SS translocator protein PopB with its chaperone PcrH from Pseudomonas aeruginosa. Banerjee A, et al. Proteins, 2014 Dec. PMID 25116453
    3. Membrane and chaperone recognition by the major translocator protein PopB of the type III secretion system of Pseudomonas aeruginosa. Discola KF, et al. J Biol Chem, 2014 Feb 7. PMID 24297169, Free PMC Article
    4. Protein binding between PcrG-PcrV and PcrH-PopB/PopD encoded by the pcrGVH-popBD operon of the Pseudomonas aeruginosa type III secretion system. Allmond LR, et al. Infect Immun, 2003 Apr. PMID 12654846, Free PMC Article
    5. Functional conservation of the effector protein translocators PopB/YopB and PopD/YopD of Pseudomonas aeruginosa and Yersinia pseudotuberculosis. Frithz-Lindsten E, et al. Mol Microbiol, 1998 Sep. PMID 9767584

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The interaction between PopB and PopD guide the assembly of a unique hetero-oligomer in membranes.
      Title: Type 3 Secretion Translocators Spontaneously Assemble a Hexadecameric Transmembrane Complex.
    2. Data suggest that PscH participates in Type III secretion system for PopB; binding sites on PcrH for PopB are primarily localized within N-terminal domain; disordered/flexible residues at N- and C-terminal domains are also involved.
      Title: Binding mode analysis of a major T3SS translocator protein PopB with its chaperone PcrH from Pseudomonas aeruginosa.
    3. the crystal structure of the complex between PcrH and an N-terminal region of PopB (residues 51-59), which reveals that PopB lies within the concave face of PcrH, employing mostly backbone residues for contact.
      Title: Membrane and chaperone recognition by the major translocator protein PopB of the type III secretion system of Pseudomonas aeruginosa.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PseudoCAP

    Function Evidence Code Pubs
    enables protein-folding chaperone binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within translocation of peptides or proteins into host IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    translocator protein PopB
    NP_250399.1
    • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      1853665..1854837
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_250399.1 translocator protein PopB [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_250399.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      O30529
      Conserved Domains (1) summary
      COG5613
      Location:1 → 390
      COG5613; Uncharacterized protein [Function unknown]
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials