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    clpX ATP-dependent protease ATP-binding subunit ClpX [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 878307, updated on 11-Sep-2024

    Summary

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    Gene symbol
    clpX
    Gene description
    ATP-dependent protease ATP-binding subunit ClpX
    Locus tag
    PA1802
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (1954815..1956095)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene trigger factor Neighboring gene ATP-dependent Clp protease proteolytic subunit Neighboring gene Lon protease Neighboring gene DNA-binding protein HU

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Alteration of protein homeostasis mediates the interaction of Pseudomonas aeruginosa with Staphylococcus aureus. Yang N, et al. Mol Microbiol, 2020 Sep. PMID 32323346
    2. ClpXP proteases positively regulate alginate overexpression and mucoid conversion in Pseudomonas aeruginosa. Qiu D, et al. Microbiology (Reading), 2008 Jul. PMID 18599839, Free PMC Article
    3. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    4. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    5. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Alteration of protein homeostasis mediates the interaction of Pseudomonas aeruginosa with Staphylococcus aureus.
      Title: Alteration of protein homeostasis mediates the interaction of Pseudomonas aeruginosa with Staphylococcus aureus.
    2. The ClpXP and ClpP2 proteins degrades the cytoplasmic portion of truncated MucA proteins to release the sequestered AlgU, which drives alginate biosynthesis.
      Title: ClpXP proteases positively regulate alginate overexpression and mucoid conversion in Pseudomonas aeruginosa.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    ATP-dependent protease ATP-binding subunit ClpX
    NP_250493.1
    • Product name confidence: class 2 (High similarity to functionally studied protein)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      1954815..1956095
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_250493.1 ATP-dependent protease ATP-binding subunit ClpX [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_250493.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A3M5DFV1
      Conserved Domains (1) summary
      PRK05342
      Location:5 → 417
      clpX; ATP-dependent Clp protease ATP-binding subunit ClpX
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9I2U0.1

    Gene LinkOut

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