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    lpxD UDP-3-O-acylglucosamine N-acyltransferase [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 880525, updated on 11-Sep-2024

    Summary

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    Gene symbol
    lpxD
    Gene description
    UDP-3-O-acylglucosamine N-acyltransferase
    Locus tag
    PA3646
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (4083444..4084505, complement)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene ribonuclease HII Neighboring gene lipid-A-disaccharide synthase Neighboring gene acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase Neighboring gene 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ Neighboring gene hypothetical protein Neighboring gene outer membrane protein Opr86

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression of the lipopolysaccharide biosynthesis gene lpxD affects biofilm formation of Pseudomonas aeruginosa. Alshalchi SA, et al. Arch Microbiol, 2015 Mar. PMID 25173672
    2. The novel hexapeptide motif found in the acyltransferases LpxA and LpxD of lipid A biosynthesis is conserved in various bacteria. Vuorio R, et al. FEBS Lett, 1994 Jan 17. PMID 8293817
    3. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    4. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    5. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Function Evidence Code Pubs
    enables acyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within lipid A biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    UDP-3-O-acylglucosamine N-acyltransferase
    NP_252336.1
    • Product name confidence: class 2 (High similarity to functionally studied protein)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      4083444..4084505 complement
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_252336.1 UDP-3-O-acylglucosamine N-acyltransferase [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_252336.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9HXY6
      Conserved Domains (1) summary
      PRK00892
      Location:6 → 341
      lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9HXY6.1

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