U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    lytB 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 879669, updated on 11-Sep-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    lytB
    Gene description
    4-hydroxy-3-methylbut-2-enyl diphosphate reductase
    Locus tag
    PA4557
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_002516.2 (5104986..5105930, complement)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene type 4 fimbrial biogenesis protein PilY1 Neighboring gene type 4 fimbrial biogenesis protein PilY2 Neighboring gene type 4 fimbrial biogenesis protein PilE Neighboring gene FkbP-type peptidyl-prolyl cis-trans isomerase Neighboring gene lipoprotein signal peptidase Neighboring gene isoleucine--tRNA ligase

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Isoprenoid biosynthesis via the methylerythritol phosphate pathway: the (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase (LytB/IspH) from Escherichia coli is a [4Fe-4S] protein. Wolff M, et al. FEBS Lett, 2003 Apr 24. PMID 12706830
    2. LytB, a novel gene of the 2-C-methyl-D-erythritol 4-phosphate pathway of isoprenoid biosynthesis in Escherichia coli. Altincicek B, et al. FEBS Lett, 2001 Jun 15. PMID 11418107
    3. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    4. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    5. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PseudoCAP

    Function Evidence Code Pubs
    enables 4-hydroxy-3-methylbut-2-enyl diphosphate reductase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within terpenoid biosynthetic process, mevalonate-independent ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    4-hydroxy-3-methylbut-2-enyl diphosphate reductase
    NP_253247.1
    • Product name confidence: class 2 (High similarity to functionally studied protein)

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      5104986..5105930 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_253247.1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_253247.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A367M7N8
      Conserved Domains (1) summary
      PRK01045
      Location:1 → 302
      ispH; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9HVM7.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials