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    ftsH cell division protein FtsH [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 881716, updated on 17-Dec-2024

    Summary

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    Gene symbol
    ftsH
    Gene description
    cell division protein FtsH
    Locus tag
    PA4751
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (5335782..5337701, complement)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene phosphoglucosamine mutase Neighboring gene dihydropteroate synthase Neighboring gene cell division protein FtsJ Neighboring gene hypothetical protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Heat-shock proteases promote survival of Pseudomonas aeruginosa during growth arrest. Basta DW, et al. Proc Natl Acad Sci U S A, 2020 Feb 25. PMID 32029587, Free PMC Article
    2. Membrane proteases and aminoglycoside antibiotic resistance. Hinz A, et al. J Bacteriol, 2011 Sep. PMID 21764915, Free PMC Article
    3. Escherichia coli FtsH is a membrane-bound, ATP-dependent protease which degrades the heat-shock transcription factor sigma 32. Tomoyasu T, et al. EMBO J, 1995 Jun 1. PMID 7781608, Free PMC Article
    4. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    5. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The heat-shock protease FtsH is generally required for growth arrest survival of Pseudomonas aeruginosa.
      Title: Heat-shock proteases promote survival of Pseudomonas aeruginosa during growth arrest.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Function Evidence Code Pubs
    enables ATP hydrolysis activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to antibiotic IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within proteolysis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cell division protein FtsH
    NP_253439.1
    • Product name confidence: class 2 (High similarity to functionally studied protein)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      5335782..5337701 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_253439.1 cell division protein FtsH [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_253439.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A0F6UHM0, A0A1S1BYI4
      Conserved Domains (1) summary
      PRK10733
      Location:1 → 639
      hflB; ATP-dependent zinc metalloprotease FtsH
    Nucleotide Protein
    Heading Accession and Version

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