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    PA5017 hypothetical protein [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 881298, updated on 24-Aug-2024

    Summary

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    Gene symbol
    PA5017
    Gene description
    hypothetical protein
    Locus tag
    PA5017
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (5641010..5643709)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene pyruvate dehydrogenase subunit E1 Neighboring gene dihydrolipoamide acetyltransferase Neighboring gene peptide methionine sulfoxide reductase Neighboring gene hypothetical protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Multiple Environmental Factors Influence the Importance of the Phosphodiesterase DipA upon Pseudomonas aeruginosa Swarming. Mattingly AE, et al. Appl Environ Microbiol, 2018 Apr 1. PMID 29427430, Free PMC Article
    2. The phosphodiesterase DipA (PA5017) is essential for Pseudomonas aeruginosa biofilm dispersion. Roy AB, et al. J Bacteriol, 2012 Jun. PMID 22493016, Free PMC Article
    3. Identification of a new gene PA5017 involved in flagella-mediated motility, chemotaxis and biofilm formation in Pseudomonas aeruginosa. Li Y, et al. FEMS Microbiol Lett, 2007 Jul. PMID 17521365
    4. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    5. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. DipA exhibits more influence on minimal medium supplemented with glutamate or glucose, where flagellar motility was negated for the dipA mutant. Conversely, a dipA-deficient mutant exhibits flagellar motility when growing with LB Lennox broth and minimal medium supplemented with Casamino Acids.
      Title: Multiple Environmental Factors Influence the Importance of the Phosphodiesterase DipA upon Pseudomonas aeruginosa Swarming.
    2. DipA (PA5017) is essential for biofilm dispersion.
      Title: The phosphodiesterase DipA (PA5017) is essential for Pseudomonas aeruginosa biofilm dispersion.
    3. These results suggested that PA5017 possibly affected flagellum-dependent motility and in turn biofilm formation via the chemotaxis signal transduction pathway.
      Title: Identification of a new gene PA5017 involved in flagella-mediated motility, chemotaxis and biofilm formation in Pseudomonas aeruginosa.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    hypothetical protein
    NP_253704.1
    • 'Product name confidence: class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences)'

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      5641010..5643709
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_253704.1 hypothetical protein PA5017 [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_253704.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      Q1AHB3
      Conserved Domains (3) summary
      COG2203
      Location:174 → 339
      FhlA; GAF domain [Signal transduction mechanisms]
      PRK10060
      Location:456 → 899
      PRK10060; cyclic di-GMP phosphodiesterase
      cl21578
      Location:347 → 465
      PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    Nucleotide Protein
    Heading Accession and Version

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