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    fabI NADH-dependent enoyl-ACP reductase [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 878311, updated on 11-Sep-2024

    Summary

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    Gene symbol
    fabI
    Gene description
    NADH-dependent enoyl-ACP reductase
    Locus tag
    PA1806
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (1961227..1962024, complement)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene tRNA-Asp Neighboring gene peptidyl-prolyl cis-trans isomerase D Neighboring gene ABC transporter ATP-binding protein Neighboring gene ABC transporter permease

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of Pseudomonas aeruginosa enoyl-acyl carrier protein reductase (FabI): a target for the antimicrobial triclosan and its role in acylated homoserine lactone synthesis. Hoang TT, et al. J Bacteriol, 1999 Sep. PMID 10464225, Free PMC Article
    2. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    3. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    4. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article
    5. A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance. Salunkhe P, et al. J Bacteriol, 2005 Jul. PMID 15995206, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Function Evidence Code Pubs
    enables enoyl-[acyl-carrier-protein] reductase activity (NAD(P)H) IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    NADH-dependent enoyl-ACP reductase
    NP_250497.1
    • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      1961227..1962024 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_250497.1 NADH-dependent enoyl-ACP reductase [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_250497.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9ZFE4
      Conserved Domains (1) summary
      COG0623
      Location:1 → 263
      FabI; Enoyl-[acyl-carrier-protein] reductase (NADH) [Lipid transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZFE4.1

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