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    PA4398 two-component sensor [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 881355, updated on 24-Aug-2024

    Summary

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    Gene symbol
    PA4398
    Gene description
    two-component sensor
    Locus tag
    PA4398
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (4927998..4930094)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene two-component response regulator Neighboring gene 2-dehydropantoate 2-reductase Neighboring gene hypothetical protein Neighboring gene hypothetical protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sensor kinase PA4398 modulates swarming motility and biofilm formation in Pseudomonas aeruginosa PA14. Strehmel J, et al. Appl Environ Microbiol, 2015 Feb. PMID 25501476, Free PMC Article
    2. Swarming of Pseudomonas aeruginosa is controlled by a broad spectrum of transcriptional regulators, including MetR. Yeung AT, et al. J Bacteriol, 2009 Sep. PMID 19592586, Free PMC Article
    3. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    4. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    5. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Sensor kinase PA4398 modulates swarming motility and biofilm formation.
      Title: Sensor kinase PA4398 modulates swarming motility and biofilm formation in Pseudomonas aeruginosa PA14.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of single-species biofilm formation on inanimate substrate ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of cell motility ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    two-component sensor
    NP_253088.1
    • 'Product name confidence: class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene)'

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      4927998..4930094
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_253088.1 two-component sensor [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_253088.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      Q9HW08
      Conserved Domains (3) summary
      COG0840
      Location:128 → 280
      Tar; Methyl-accepting chemotaxis protein [Cell motility, Signal transduction mechanisms]
      PRK11360
      Location:280 → 669
      PRK11360; two-component system sensor histidine kinase AtoS
      cd06225
      Location:188 → 233
      HAMP; Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain
    Nucleotide Protein
    Heading Accession and Version

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