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    hflC protease subunit HflC [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 878721, updated on 24-Aug-2024

    Summary

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    Gene symbol
    hflC
    Gene description
    protease subunit HflC
    Locus tag
    PA4941
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (5544917..5545786, complement)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene ATP phosphoribosyltransferase Neighboring gene hypothetical protein Neighboring gene protease subunit HflK Neighboring gene GTP-binding protein Neighboring gene RNA-binding protein Hfq

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A protease complex in the Escherichia coli plasma membrane: HflKC (HflA) forms a complex with FtsH (HflB), regulating its proteolytic activity against SecY. Kihara A, et al. EMBO J, 1996 Nov 15. PMID 8947034, Free PMC Article
    2. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    3. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    4. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article
    5. A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance. Salunkhe P, et al. J Bacteriol, 2005 Jul. PMID 15995206, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of proteolysis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protease subunit HflC
    NP_253628.1
    • Product name confidence: class 2 (High similarity to functionally studied protein)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      5544917..5545786 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_253628.1 protease subunit HflC [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_253628.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      Q9HUM3
      Conserved Domains (1) summary
      cd03405
      Location:22 → 272
      SPFH_HflC; High frequency of lysogenization C (HflC) family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
    Nucleotide Protein
    Heading Accession and Version

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