FCGR2B Fc gamma receptor IIb [Homo sapiens (human)] - Gene

Summary

Official Symbol: FCGR2Bprovided by HGNC
Official Full Name: Fc gamma receptor IIbprovided by HGNC
Primary source: HGNC:HGNC:3618
See related: Ensembl:ENSG00000072694 MIM:604590; AllianceGenome:HGNC:3618
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: CD32; FCG2; CD32B; FCGR2; IGFR2; FCGR2C; FcGRIIB; FcRII-c; FcgammaRIIb
Summary: The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Expression: Biased expression in placenta (RPKM 92.9), appendix (RPKM 9.6) and 6 other tissues See more
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 1q23.3

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	1	NC_000001.11 (161647243..161678654)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	1	NC_060925.1 (160991589..161022983)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	1	NC_000001.10 (161617033..161648444)

Chromosome 1 - NC_000001.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Tissue-specific circular RNA induction during human fetal development
Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
BioProject: PRJNA270632
Publication: PMID 26076956
Analysis date: Mon Apr 2 22:54:59 2018

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

FcgammaRIIB Is an Immune Checkpoint Limiting the Activity of Treg-Targeting Antibodies in the Tumor Microenvironment.
Title: FcγRIIB Is an Immune Checkpoint Limiting the Activity of Treg-Targeting Antibodies in the Tumor Microenvironment.
Evaluation of the FCGR2B polymorphism in children with immune thrombocytopenia.
Title: Evaluation of the FCGR2B polymorphism in children with immune thrombocytopenia.
C-reactive protein impairs immune response of CD8[+] T cells via FcgammaRIIb-p38MAPK-ROS axis in multiple myeloma.
Title: C-reactive protein impairs immune response of CD8(+) T cells via FcγRIIb-p38MAPK-ROS axis in multiple myeloma.
FCGR2B as a prognostic and immune microenvironmental marker for gliomas based on transcriptomic analysis.
Title: FCGR2B as a prognostic and immune microenvironmental marker for gliomas based on transcriptomic analysis.
FcgammaRIIB expression increases during primary biliary cholangitis.
Title: FcγRIIB expression increases during primary biliary cholangitis.
FcgammaRIIB expressed on CD8[+] T cells limits responsiveness to PD-1 checkpoint inhibition in cancer.
Title: FcγRIIB expressed on CD8(+) T cells limits responsiveness to PD-1 checkpoint inhibition in cancer.
Mutation of the TGN1412 anti-CD28 monoclonal antibody lower hinge confers specific FcgammaRIIb binding and retention of super-agonist activity.
Title: Mutation of the TGN1412 anti-CD28 monoclonal antibody lower hinge confers specific FcγRIIb binding and retention of super-agonist activity.
FCGR2A as one novel potential target for poor survival prognosis of clear cell renal cell carcinoma.
Title: FCGR2A as one novel potential target for poor survival prognosis of clear cell renal cell carcinoma.
An auxiliary binding interface of SHIP2-SH2 for Y292-phosphorylated FcgammaRIIB reveals diverse recognition mechanisms for tyrosine-phosphorylated receptors involved in different cell signaling pathways.
Title: An auxiliary binding interface of SHIP2-SH2 for Y292-phosphorylated FcγRIIB reveals diverse recognition mechanisms for tyrosine-phosphorylated receptors involved in different cell signaling pathways.
FcgammaRIIB potentiates differentiation of myeloid-derived suppressor cells to mediate tumor immunoescape.
Title: FcγRIIB potentiates differentiation of myeloid-derived suppressor cells to mediate tumor immunoescape.

Submit: New GeneRIF Correction See all GeneRIFs (166)

Phenotypes

Go to the top of the page Help

Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description	Tests
Malaria, susceptibility to MedGen: C1970028 OMIM: 611162 GeneReviews: Not available	Compare labs
Systemic lupus erythematosus MedGen: C0024141 OMIM: 152700 GeneReviews: Not available	Compare labs

EBI GWAS Catalog

Description
Genome-wide association study identifies multiple loci influencing human serum metabolite levels. EBI GWAS Catalog EBI GWAS CatalogPubMed
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. EBI GWAS Catalog EBI GWAS CatalogPubMed
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. EBI GWAS Catalog EBI GWAS CatalogPubMed

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

HIV-1 interactions

Go to the top of the page Help

Protein interactions

Protein	Gene	Interaction	Pubs
Envelope surface glycoprotein gp120	env	IgG2 and IgG4 bind more poorly to enzymatically deglycosylated recombinant gp120 (rgp120) than to unchanged rgp120	PubMed
Nef	nef	HIV-1 Nef downregulates Fc-gamma Receptor II in human monocytes/macrophages	PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

RH66834 (e-PCR)
- UniSTS:29229

G06355 (e-PCR)
- UniSTS:73835

RH69121 (e-PCR)
- UniSTS:32170

PMC26659P1 (e-PCR)
- UniSTS:272343

GDB:190031 (e-PCR)
- UniSTS:155610

RH11110 (e-PCR)
- UniSTS:68838

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables IgG binding	IBA Inferred from Biological aspect of Ancestor more info
enables IgG binding	IDA Inferred from Direct Assay more info	PubMed
enables IgG receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables amyloid-beta binding	IPI Inferred from Physical Interaction more info	PubMed
enables amyloid-beta binding	TAS Traceable Author Statement more info	PubMed
enables low-affinity IgG receptor activity	IDA Inferred from Direct Assay more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein-containing complex binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in Fc-gamma receptor signaling pathway	IDA Inferred from Direct Assay more info	PubMed
involved_in antibody-dependent cellular cytotoxicity	IBA Inferred from Biological aspect of Ancestor more info
involved_in antigen processing and presentation of exogenous peptide antigen via MHC class II	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in cell surface receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in cellular response to amyloid-beta	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in cellular response to molecule of bacterial origin	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in cerebellum development	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in defense response	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in follicular B cell differentiation	TAS Traceable Author Statement more info	PubMed
involved_in follicular dendritic cell activation	TAS Traceable Author Statement more info	PubMed
involved_in immune complex clearance by monocytes and macrophages	TAS Traceable Author Statement more info	PubMed
involved_in immune effector process	IDA Inferred from Direct Assay more info	PubMed
involved_in immunoglobulin mediated immune response	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in inflammatory response	TAS Traceable Author Statement more info	PubMed
NOT involved_in mast cell activation	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in mature B cell differentiation involved in immune response	TAS Traceable Author Statement more info	PubMed
involved_in negative regulation of B cell activation	TAS Traceable Author Statement more info	PubMed
involved_in negative regulation of B cell proliferation	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in negative regulation of B cell receptor signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of acute inflammatory response to antigenic stimulus	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in negative regulation of antibody-dependent cellular cytotoxicity	TAS Traceable Author Statement more info	PubMed
involved_in negative regulation of cytokine production	TAS Traceable Author Statement more info	PubMed
involved_in negative regulation of cytotoxic T cell degranulation	TAS Traceable Author Statement more info	PubMed
involved_in negative regulation of dendritic cell antigen processing and presentation	TAS Traceable Author Statement more info	PubMed
involved_in negative regulation of dendritic cell differentiation	TAS Traceable Author Statement more info	PubMed
involved_in negative regulation of humoral immune response mediated by circulating immunoglobulin	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in negative regulation of immune response	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in negative regulation of immunoglobulin production	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in negative regulation of interleukin-10 production	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in negative regulation of macrophage activation	TAS Traceable Author Statement more info	PubMed
involved_in negative regulation of neutrophil activation	TAS Traceable Author Statement more info	PubMed
involved_in negative regulation of phagocytosis	TAS Traceable Author Statement more info	PubMed
involved_in negative regulation of type I hypersensitivity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in phagocytosis	IDA Inferred from Direct Assay more info	PubMed
involved_in phagocytosis, engulfment	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in positive regulation of JNK cascade	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in positive regulation of humoral immune response	TAS Traceable Author Statement more info	PubMed
involved_in positive regulation of phagocytosis	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of phagocytosis	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in positive regulation of response to endoplasmic reticulum stress	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in positive regulation of tumor necrosis factor production	IBA Inferred from Biological aspect of Ancestor more info
involved_in receptor-mediated endocytosis	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of B cell antigen processing and presentation	TAS Traceable Author Statement more info	PubMed
involved_in regulation of adaptive immune response	TAS Traceable Author Statement more info	PubMed
involved_in regulation of dendritic spine maintenance	IGI Inferred from Genetic Interaction more info	PubMed
involved_in regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in regulation of immune complex clearance by monocytes and macrophages	TAS Traceable Author Statement more info	PubMed
involved_in regulation of innate immune response	TAS Traceable Author Statement more info	PubMed
involved_in regulation of signaling receptor activity	TAS Traceable Author Statement more info	PubMed
involved_in response to bacterium	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Component	Evidence Code	Pubs
located_in cell body	ISS Inferred from Sequence or Structural Similarity more info	PubMed
located_in dendritic spine	ISS Inferred from Sequence or Structural Similarity more info	PubMed
is_active_in external side of plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in external side of plasma membrane	ISS Inferred from Sequence or Structural Similarity more info	PubMed
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	TAS Traceable Author Statement more info

General protein information

Go to the top of the page Help

Preferred Names: low affinity immunoglobulin gamma Fc region receptor II-b

Names: CDw32; Fc fragment of IgG receptor IIb; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); Fc gamma RIIb; Fc-gamma RII-c; Fc-gamma-RIIc; IgG Fc receptor II-c; Low affinity immunoglobulin gamma Fc region receptor II-c; fc-gamma RII-b; fc-gamma-RIIb; fcRII-b; igG Fc receptor II-b

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

NG_023318.2 RefSeqGene

Range

20902..36413

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001002273.3 → NP_001002273.1 low affinity immunoglobulin gamma Fc region receptor II-b isoform 2 precursor

See identical proteins and their annotated locations for NP_001002273.1

Status: REVIEWED

Description

Transcript Variant: This variant (2) lacks an alternate in-frame exon and uses an alternate in-frame splice junction at the 5' end of an exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.

Source sequence(s)

AL451067

UniProtKB/Swiss-Prot

O00523, O00524, O00525, P31995

Conserved Domains (2) summary

cd05752
Location:49 → 127

Ig1_FcgammaR_like; Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins

cd05753
Location:131 → 213

Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins
NM_001002274.3 → NP_001002274.1 low affinity immunoglobulin gamma Fc region receptor II-b isoform 3 precursor

See identical proteins and their annotated locations for NP_001002274.1

Status: REVIEWED

Description

Transcript Variant: This variant (3) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (3) has the same N- and C-termini but is shorter compared to isoform 1.

Source sequence(s)

AL451067

Consensus CDS

CCDS30925.1

UniProtKB/Swiss-Prot

O00523, O00524, O00525, P31995

Related

ENSP00000236937.9, ENST00000236937.13

Conserved Domains (2) summary

cd05752
Location:50 → 128

Ig1_FcgammaR_like; Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins

cd05753
Location:132 → 214

Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins
NM_001002275.3 → NP_001002275.1 low affinity immunoglobulin gamma Fc region receptor II-b isoform 4 precursor

See identical proteins and their annotated locations for NP_001002275.1

Status: REVIEWED

Description

Transcript Variant: This variant (4) uses an alternate in-frame splice junction at the 5' end of an exon compared to variant 1. The resulting isoform (4) has the same N- and C-termini but is 1 aa shorter compared to isoform 1.

Source sequence(s)

AL451067

UniProtKB/Swiss-Prot

P31994

Conserved Domains (2) summary

cd05752
Location:49 → 127

Ig1_FcgammaR_like; Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins

cd05753
Location:131 → 213

Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins
NM_001190828.2 → NP_001177757.1 low affinity immunoglobulin gamma Fc region receptor II-b isoform 5 precursor

See identical proteins and their annotated locations for NP_001177757.1

Status: REVIEWED

Description

Transcript Variant: This variant (5) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (5) has the same N- and C-termini but is shorter compared to isoform 1.

Source sequence(s)

AL451067

Consensus CDS

CCDS53414.1

UniProtKB/Swiss-Prot

P31994

Related

ENSP00000356938.4, ENST00000367961.8

Conserved Domains (3) summary

cd05752
Location:43 → 121

Ig1_FcgammaR_like; Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins

cd05753
Location:125 → 207

Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins

smart00410
Location:131 → 207

IG_like; Immunoglobulin like
NM_001386000.1 → NP_001372929.1 low affinity immunoglobulin gamma Fc region receptor II-b isoform 6

Status: REVIEWED

Source sequence(s)

AL451067

Conserved Domains (2) summary

cd05752
Location:42 → 120

Ig1_FcgammaR_like; First immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs), and similar domains

cd05753
Location:124 → 206

Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs), and similar domains
NM_001386001.1 → NP_001372930.1 low affinity immunoglobulin gamma Fc region receptor II-b isoform 7 precursor

Status: REVIEWED

Source sequence(s)

AL451067

Conserved Domains (2) summary

cd05752
Location:43 → 121

Ig1_FcgammaR_like; First immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs), and similar domains

cd05753
Location:125 → 207

Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs), and similar domains
NM_001386002.1 → NP_001372931.1 low affinity immunoglobulin gamma Fc region receptor II-b isoform 8

Status: REVIEWED

Source sequence(s)

AL451067

Conserved Domains (2) summary

cd05752
Location:42 → 120

Ig1_FcgammaR_like; First immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs), and similar domains

cd05753
Location:124 → 206

Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs), and similar domains
NM_001386003.1 → NP_001372932.1 low affinity immunoglobulin gamma Fc region receptor II-b isoform 9 precursor

Status: REVIEWED

Source sequence(s)

AL451067

Conserved Domains (2) summary

cd05752
Location:50 → 128

Ig1_FcgammaR_like; First immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs), and similar domains

cd05753
Location:132 → 214

Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs), and similar domains
NM_001386004.1 → NP_001372933.1 low affinity immunoglobulin gamma Fc region receptor II-b isoform 10

Status: REVIEWED

Source sequence(s)

AL451067

Conserved Domains (2) summary

cd05752
Location:42 → 120

Ig1_FcgammaR_like; First immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs), and similar domains

cd05753
Location:124 → 206

Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs), and similar domains
NM_001386005.1 → NP_001372934.1 low affinity immunoglobulin gamma Fc region receptor II-b isoform 11 precursor

Status: REVIEWED

Source sequence(s)

AL451067

Conserved Domains (2) summary

cd05752
Location:50 → 128

Ig1_FcgammaR_like; First immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs), and similar domains

cd05753
Location:132 → 214

Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs), and similar domains
NM_001386006.1 → NP_001372935.1 low affinity immunoglobulin gamma Fc region receptor II-b isoform 12 precursor

Status: REVIEWED

Source sequence(s)

AL451067

Conserved Domains (2) summary

cd05752
Location:43 → 121

Ig1_FcgammaR_like; First immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs), and similar domains

cd05753
Location:125 → 207

Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs), and similar domains
NM_001394477.1 → NP_001381406.1 low affinity immunoglobulin gamma Fc region receptor II-b isoform 1 precursor

Status: REVIEWED

Description

Transcript Variant: Variants 1 and 14 encode the same isoform (1).

Source sequence(s)

AL451067

Consensus CDS

CCDS30924.1

UniProtKB/Swiss-Prot

A6H8N3, O95649, P31994, Q53X85, Q5VXA9, Q8NIA1

Related

ENSP00000351497.5, ENST00000358671.10

Conserved Domains (2) summary

cd05752
Location:50 → 128

Ig1_FcgammaR_like; First immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs), and similar domains

cd05753
Location:132 → 214

Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs), and similar domains
NM_004001.5 → NP_003992.3 low affinity immunoglobulin gamma Fc region receptor II-b isoform 1 precursor

See identical proteins and their annotated locations for NP_003992.3

Status: REVIEWED

Description

Transcript Variant: This variant (1) encodes the longest isoform (1).

Source sequence(s)

AL451067

Consensus CDS

CCDS30924.1

UniProtKB/Swiss-Prot

A6H8N3, O95649, P31994, Q53X85, Q5VXA9, Q8NIA1

Conserved Domains (2) summary

cd05752
Location:50 → 128

Ig1_FcgammaR_like; First immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs), and similar domains

cd05753
Location:132 → 214

Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs), and similar domains

RNA

NR_169827.1 RNA Sequence

Status: REVIEWED

Source sequence(s)

AL451067

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

NC_000001.11 Reference GRCh38.p14 Primary Assembly

Range

161647243..161678654

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_024454047.2 → XP_024309815.1 low affinity immunoglobulin gamma Fc region receptor II-b isoform X1

Conserved Domains (2) summary

cd05752
Location:50 → 128

Ig1_FcgammaR_like; Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins

cd05753
Location:132 → 214

Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins