IPW imprinted in Prader-Willi syndrome [Homo sapiens (human)] - Gene

Summary

Official Symbol: IPWprovided by HGNC
Official Full Name: imprinted in Prader-Willi syndromeprovided by HGNC
Primary source: HGNC:HGNC:6109
See related: MIM:601491; AllianceGenome:HGNC:6109
Gene type: ncRNA
RefSeq status: REVIEWED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: NCRNA00002
Summary: This gene is non-protein coding, is expressed exclusively from the paternal allele, and may play a role in the imprinting process. Mutations in this gene are associated with Prader-Willi syndrome. [provided by RefSeq, May 2010]
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Genomic context

Location:: 15q11.2

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	15	NC_000015.10 (25116545..25122476)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	15	NC_060939.1 (22853200..22859127)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	15	NC_000015.9 (25361692..25367623)

Chromosome 15 - NC_000015.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Tissue-specific circular RNA induction during human fetal development
Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
BioProject: PRJNA270632
Publication: PMID 26076956
Analysis date: Mon Apr 2 22:54:59 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Long Noncoding RNA IPW Is a Novel Diagnostic and Predictive Biomarker in Lung Adenocarcinoma.
Title: Long Noncoding RNA IPW Is a Novel Diagnostic and Predictive Biomarker in Lung Adenocarcinoma.
LncRNA IPW inhibits growth of ductal carcinoma in situ by downregulating ID2 through miR-29c.
Title: LncRNA IPW inhibits growth of ductal carcinoma in situ by downregulating ID2 through miR-29c.

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Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description	Tests
Prader-Willi syndrome MedGen: C0032897 OMIM: 176270 GeneReviews: Prader-Willi Syndrome	Compare labs

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

GDB:424492 (e-PCR)
- UniSTS:157194

SHGC-132610 (e-PCR)
- UniSTS:185367

SHGC-36523 (e-PCR)
- UniSTS:10386

G44340 (e-PCR)
- UniSTS:95127

A003A06 (e-PCR)
- UniSTS:42142

G60271 (e-PCR)
- UniSTS:137376

D15S903 (e-PCR)
- UniSTS:23719

D15S618E (e-PCR)
- UniSTS:149961

STS-H93310 (e-PCR)
- UniSTS:81372

STS-N21972 (e-PCR)
- UniSTS:4843

Other Names

imprinted in Prader-Willi syndrome (non-protein coding)
non-protein coding RNA 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.