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    Zc3hc1 zinc finger, C3HC-type containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 296957, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zc3hc1provided by RGD
    Official Full Name
    zinc finger, C3HC-type containing 1provided by RGD
    Primary source
    RGD:1561099
    See related
    EnsemblRapid:ENSRNOG00000010154 AllianceGenome:RGD:1561099
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1561099
    Summary
    Predicted to enable protein kinase binding activity. Predicted to be located in nuclear membrane and nucleoplasm. Predicted to be part of nuclear pore nuclear basket. Predicted to be active in nucleus. Orthologous to human ZC3HC1 (zinc finger C3HC-type containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 123.1), Spleen (RPKM 82.7) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Zc3hc1 in Genome Data Viewer
    Location:
    4q22
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (59957402..59979336, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (58989989..59011925, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (57684678..57706613, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene ubiquitin-conjugating enzyme E2H Neighboring gene small nucleolar RNA SNORA32 Neighboring gene kelch domain containing 10 Neighboring gene uncharacterized LOC134486570 Neighboring gene uncharacterized LOC108350685

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in nuclear membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     
    part_of nuclear pore nuclear basket ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    zinc finger C3HC-type protein 1
    Names
    nuclear-interacting partner of ALK
    zinc finger, C3HC-type 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001127293.1NP_001120765.1  zinc finger C3HC-type protein 1

      See identical proteins and their annotated locations for NP_001120765.1

      Status: PROVISIONAL

      Source sequence(s)
      BC166834
      UniProtKB/TrEMBL
      A0A140UHX2, A0A8I6AJ97, B2RYM6, F1MAI0
      Related
      ENSRNOP00000013606.8, ENSRNOT00000013604.9
      Conserved Domains (2) summary
      pfam07967
      Location:73201
      zf-C3HC; C3HC zinc finger-like
      pfam08600
      Location:248337
      Rsm1; Rsm1-like

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      59957402..59979336 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)