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    Mrps18a mitochondrial ribosomal protein S18A [ Mus musculus (house mouse) ]

    Gene ID: 68565, updated on 27-Nov-2024

    Summary

    Official Symbol
    Mrps18aprovided by MGI
    Official Full Name
    mitochondrial ribosomal protein S18Aprovided by MGI
    Primary source
    MGI:MGI:1915815
    See related
    Ensembl:ENSMUSG00000023967 AllianceGenome:MGI:1915815
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1110004O20Rik
    Summary
    Predicted to enable small ribosomal subunit rRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; heart; liver; and pancreas epithelium. Orthologous to human MRPS18A (mitochondrial ribosomal protein S18A). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in placenta adult (RPKM 35.9), kidney adult (RPKM 35.7) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Mrps18a in Genome Data Viewer
    Location:
    17 C; 17 22.86 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (46421930..46439834)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (46111004..46128908)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_42657 Neighboring gene vascular endothelial growth factor A Neighboring gene STARR-positive B cell enhancer ABC_E5613 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:46210901-46211088 Neighboring gene polymerase (RNA) II (DNA directed) polypeptide K pseudogene Neighboring gene radial spoke head 9 homolog (Chlamydomonas) Neighboring gene MAD2L1 binding protein Neighboring gene STARR-positive B cell enhancer ABC_E5614 Neighboring gene STARR-positive B cell enhancer ABC_E5615 Neighboring gene GTP binding protein 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC66832

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables small ribosomal subunit rRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial translation ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in mitochondrial translation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    part_of mitochondrial large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    part_of mitochondrial large ribosomal subunit NAS
    Non-traceable Author Statement
    more info
    PubMed 
    part_of mitochondrial small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of mitochondrial small ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    part_of mitochondrial small ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    large ribosomal subunit protein mL66
    Names
    28S ribosomal protein S18-3, mitochondrial
    28S ribosomal protein S18a, mitochondrial
    MRP-S18-3
    MRP-S18-a
    S18mt-a

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026768.3NP_081044.1  large ribosomal subunit protein mL66 precursor

      See identical proteins and their annotated locations for NP_081044.1

      Status: PROVISIONAL

      Source sequence(s)
      AC110562
      Consensus CDS
      CCDS28819.1
      UniProtKB/Swiss-Prot
      Q8R3H2, Q99N85, Q9D1J6
      UniProtKB/TrEMBL
      Q5U5I3
      Related
      ENSMUSP00000024763.4, ENSMUST00000024763.10
      Conserved Domains (1) summary
      pfam01084
      Location:78128
      Ribosomal_S18; Ribosomal protein S18

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      46421930..46439834
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)