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    Erv4 endogenous retroviral sequence 4 (with leucine tRNA primer) [ Mus musculus (house mouse) ]

    Gene ID: 27282, updated on 17-Aug-2024

    Summary

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    Official Symbol
    Erv4provided by MGI
    Official Full Name
    endogenous retroviral sequence 4 (with leucine tRNA primer)provided by MGI
    Primary source
    MGI:MGI:1351467
    Gene type
    other
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MuERV-L
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    Genomic context

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    Location:
    chromosome: 6

    Bibliography

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    Related articles in PubMed

    1. Murine endogenous retrovirus MuERV-L is the progenitor of the "orphan" epsilon viruslike particles of the early mouse embryo. Ribet D, et al. J Virol, 2008 Feb. PMID 18045933, Free PMC Article
    2. MuERV-L is one of the earliest transcribed genes in mouse one-cell embryos. Kigami D, et al. Biol Reprod, 2003 Feb. PMID 12533431
    3. Cloning of a new murine endogenous retrovirus, MuERV-L, with strong similarity to the human HERV-L element and with a gag coding sequence closely related to the Fv1 restriction gene. Bénit L, et al. J Virol, 1997 Jul. PMID 9188643, Free PMC Article
    4. Elevated RIF1 participates in the epigenetic abnormalities of zygotes by regulating histone modifications on MuERV-L in obese mice. Huang J, et al. Mol Med, 2022 Feb 5. PMID 35123389, Free PMC Article
    5. Role of protein synthesis in the development of a transcriptionally permissive state in one-cell stage mouse embryos. Wang Q, et al. Biol Reprod, 2001 Sep. PMID 11514337

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Elevated RIF1 participates in the epigenetic abnormalities of zygotes by regulating histone modifications on MuERV-L in obese mice.
      Title: Elevated RIF1 participates in the epigenetic abnormalities of zygotes by regulating histone modifications on MuERV-L in obese mice.
    2. Inhibiting the first round increased the expression levels of hsp70.1, eif-1a and zscan4d but decreased that of muerv, while inhibiting the second round increased the expression levels of all four genes.
      Title: Roles of the first and second round of DNA replication in the regulation of zygotic gene activation in mice.
    Submit: New GeneRIF Correction

    General gene information

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    Other Names

    • endogenous retroviral sequence 4 (with leucine t-RNA primer)
    Nucleotide Protein Strain
    Heading Accession and Version

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