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    TFF1 trefoil factor 1 [ Sus scrofa (pig) ]

    Gene ID: 780401, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TFF1provided by VGNC
    Official Full Name
    trefoil factor 1provided by VGNC
    Primary source
    VGNC:VGNC:93919
    See related
    Ensembl:ENSSSCG00000034731
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    human mouse all
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    Genomic context

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    See TFF1 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 13 NC_010455.5 (205687558..205691512, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 13 NC_010455.4 (216090047..216093946, complement)

    Chromosome 13 - NC_010455.5Genomic Context describing neighboring genes Neighboring gene trefoil factor 3 Neighboring gene trefoil factor 2 Neighboring gene transmembrane serine protease 3 Neighboring gene ubiquitin associated and SH3 domain containing A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Intestinal expression of TFF and related genes during postnatal development in a piglet probiotic trial. Scholven J, et al. Cell Physiol Biochem, 2009. PMID 19255509
    2. Expression of mucins and trefoil factor family protein-1 in the colon of pigs naturally infected with Salmonella typhimurium. Kim CH, et al. J Comp Pathol, 2009 Jan. PMID 19064270
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Weaning was not associated with fifferential TFF1 expression in the distal jejunum and ileum.
      Title: Intestinal expression of TFF and related genes during postnatal development in a piglet probiotic trial.
    2. Colon from infected swine had increased expression of MUC5AC and TFF1 relative to controls.
      Title: Expression of mucins and trefoil factor family protein-1 in the colon of pigs naturally infected with Salmonella typhimurium.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in maintenance of gastrointestinal epithelium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    trefoil factor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010455.5 Reference Sscrofa11.1 Primary Assembly

      Range
      205687558..205691512 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003358973.3 → XP_003359021.1  trefoil factor 1

      UniProtKB/TrEMBL
      A0A286ZIY1, A0A4X1TFR4, A0A8D0SR84, A0A8D1E8G3
      Related
      ENSSSCP00000031403.1, ENSSSCT00000057760.3
      Conserved Domains (1) summary
      smart00018
      Location:26 → 71
      PD; P or trefoil or TFF domain
    Nucleotide Protein
    Heading Accession and Version

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