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    VRK3 VRK serine/threonine kinase 3 [ Sus scrofa (pig) ]

    Gene ID: 100523004, updated on 3-Dec-2024

    Summary

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    Official Symbol
    VRK3provided by VGNC
    Official Full Name
    VRK serine/threonine kinase 3provided by VGNC
    Primary source
    VGNC:VGNC:98409
    See related
    Ensembl:ENSSSCG00000003204
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Ubiquitous expression in lung (RPKM 4.6), ovary (RPKM 4.4) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See VRK3 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 6 NC_010448.4 (54973734..55041607, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 6 NC_010448.3 (50754926..50791580, complement)

    Chromosome 6 - NC_010448.4Genomic Context describing neighboring genes Neighboring gene interleukin 4 induced 1 Neighboring gene nucleoporin 62 Neighboring gene activating transcription factor 5 Neighboring gene sialic acid binding Ig like lectin 11 Neighboring gene zinc finger protein 420 Neighboring gene zinc finger protein 473 Neighboring gene IZUMO family member 2 Neighboring gene cytochrome b-c1 complex subunit 7 pseudogene Neighboring gene myosin heavy chain 14

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    inactive serine/threonine-protein kinase VRK3
    Names
    vaccinia related kinase 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010448.4 Reference Sscrofa11.1 Primary Assembly

      Range
      54973734..55041607 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_013998684.2 → XP_013854138.2  inactive serine/threonine-protein kinase VRK3

      UniProtKB/TrEMBL
      A0A287AHL0, A0A4X1VWE3, A0A8D0IRN0
      Conserved Domains (2) summary
      pfam13240
      Location:3 → 25
      zinc_ribbon_2; zinc-ribbon domain
      cl21453
      Location:147 → 449
      PKc_like; Protein Kinases, catalytic domain

    2. XM_021094775.1 → XP_020950434.1  inactive serine/threonine-protein kinase VRK3

      UniProtKB/TrEMBL
      A0A287AHL0, A0A4X1VWE3, A0A8D0IRN0
      Conserved Domains (2) summary
      pfam13240
      Location:3 → 25
      zinc_ribbon_2; zinc-ribbon domain
      cl21453
      Location:147 → 449
      PKc_like; Protein Kinases, catalytic domain

    3. XM_021094776.1 → XP_020950435.1  inactive serine/threonine-protein kinase VRK3

      UniProtKB/TrEMBL
      A0A287AHL0, A0A4X1VWE3, A0A8D0IRN0
      Conserved Domains (2) summary
      pfam13240
      Location:3 → 25
      zinc_ribbon_2; zinc-ribbon domain
      cl21453
      Location:147 → 449
      PKc_like; Protein Kinases, catalytic domain

    4. XM_003127354.5 → XP_003127402.2  inactive serine/threonine-protein kinase VRK3

      UniProtKB/TrEMBL
      A0A287AHL0, A0A4X1VWE3, A0A8D0IRN0
      Conserved Domains (2) summary
      pfam13240
      Location:3 → 25
      zinc_ribbon_2; zinc-ribbon domain
      cl21453
      Location:147 → 449
      PKc_like; Protein Kinases, catalytic domain

    5. XM_013998683.2 → XP_013854137.2  inactive serine/threonine-protein kinase VRK3

      UniProtKB/TrEMBL
      A0A287AHL0, A0A4X1VWE3, A0A8D0IRN0
      Conserved Domains (2) summary
      pfam13240
      Location:3 → 25
      zinc_ribbon_2; zinc-ribbon domain
      cl21453
      Location:147 → 449
      PKc_like; Protein Kinases, catalytic domain

    6. XM_005664766.2 → XP_005664823.2  inactive serine/threonine-protein kinase VRK3

      UniProtKB/TrEMBL
      A0A287AHL0, A0A4X1VWE3, A0A8D0IRN0
      Conserved Domains (2) summary
      pfam13240
      Location:3 → 25
      zinc_ribbon_2; zinc-ribbon domain
      cl21453
      Location:147 → 449
      PKc_like; Protein Kinases, catalytic domain

    7. XM_003127353.5 → XP_003127401.2  inactive serine/threonine-protein kinase VRK3

      UniProtKB/TrEMBL
      A0A287AHL0, A0A4X1VWE3, A0A8D0IRN0
      Conserved Domains (2) summary
      pfam13240
      Location:3 → 25
      zinc_ribbon_2; zinc-ribbon domain
      cl21453
      Location:147 → 449
      PKc_like; Protein Kinases, catalytic domain

    8. XM_013998685.2 → XP_013854139.2  inactive serine/threonine-protein kinase VRK3

      UniProtKB/TrEMBL
      A0A287AHL0, A0A4X1VWE3, A0A8D0IRN0
      Related
      ENSSSCP00000053883.3, ENSSSCT00000064826.3
      Conserved Domains (2) summary
      pfam13240
      Location:3 → 25
      zinc_ribbon_2; zinc-ribbon domain
      cl21453
      Location:147 → 449
      PKc_like; Protein Kinases, catalytic domain

    9. XM_021094777.1 → XP_020950436.1  inactive serine/threonine-protein kinase VRK3

      UniProtKB/TrEMBL
      A0A287AHL0, A0A4X1VWE3, A0A8D0IRN0
      Related
      ENSSSCP00000043376.1, ENSSSCT00000055317.3
      Conserved Domains (2) summary
      pfam13240
      Location:3 → 25
      zinc_ribbon_2; zinc-ribbon domain
      cl21453
      Location:147 → 449
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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