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    NELFB negative elongation factor complex member B [ Sus scrofa (pig) ]

    Gene ID: 100514560, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NELFBprovided by VGNC
    Official Full Name
    negative elongation factor complex member Bprovided by VGNC
    Primary source
    VGNC:VGNC:90681
    See related
    Ensembl:ENSSSCG00000005846
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Also known as
    COBRA1
    Expression
    Ubiquitous expression in ovary (RPKM 30.3), spleen (RPKM 21.4) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See NELFB in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) Unplaced Scaffold NW_018084833.1 (647556..656244, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 1 NC_010443.4 (314117252..314125940, complement)

    NW_018084833.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106507771 Neighboring gene torsin family 4 member A Neighboring gene sperm-tail PG-rich repeat containing 3 Neighboring gene ciliary microtubule inner protein 2A Neighboring gene tubulin beta 4B class IVb

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Translational Initiation at a Non-AUG Start Codon for Human and Mouse Negative Elongation Factor-B. Pan H, et al. PLoS One, 2015. PMID 26010750, Free PMC Article
    2. Porcine gene discovery by normalized cDNA-library sequencing and EST cluster assembly. Fahrenkrug SC, et al. Mamm Genome, 2002 Aug. PMID 12226715
    3. Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags. Gorodkin J, et al. Genome Biol, 2007. PMID 17407547, Free PMC Article
    4. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in negative regulation of transcription elongation by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of NELF complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    negative elongation factor B
    Names
    cofactor of BRCA1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001310162.1 → NP_001297091.1  negative elongation factor B

      Status: VALIDATED

      Source sequence(s)
      AEMK02000682
      UniProtKB/TrEMBL
      A0A8D1I0L7
      Related
      ENSSSCP00000068497.2, ENSSSCT00000077536.2
      Conserved Domains (2) summary
      pfam01391
      Location:7 → 42
      Collagen; Collagen triple helix repeat (20 copies)
      pfam06209
      Location:158 → 629
      COBRA1; Cofactor of BRCA1 (COBRA1)

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NW_018084833.1 Reference Sscrofa11.1 Primary Assembly

      Range
      647556..656244 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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    Research Materials